Neuronal injuries in cerebral infarction and ischemic stroke: From mechanisms to treatment

Y Zhao, X Zhang, X Chen… - … journal of molecular …, 2022 - spandidos-publications.com
Stroke is the leading cause of disabilities and cognitive deficits, accounting for 5.2% of all
mortalities worldwide. Transient or permanent occlusion of cerebral vessels leads to …

Management of acute ischemic stroke

F Herpich, F Rincon - Critical care medicine, 2020 - journals.lww.com
Objectives: Concise “synthetic” review of the state of the art of management of acute
ischemic stroke. Data Sources: Available literature on PubMed. Study Selection: We …

Emerging neuroprotective strategies for the treatment of ischemic stroke: An overview of clinical and preclinical studies

S Paul, E Candelario-Jalil - Experimental neurology, 2021 - Elsevier
Stroke is the leading cause of disability and thesecond leading cause of death worldwide.
With the global population aged 65 and over growing faster than all other age groups, the …

[HTML][HTML] Impact of the natural compound urolithin A on health, disease, and aging

D D'Amico, PA Andreux, P Valdés, A Singh… - Trends in molecular …, 2021 - cell.com
Urolithin A (UA) is a natural compound produced by gut bacteria from ingested ellagitannins
(ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranate …

Macrophage‐disguised manganese dioxide nanoparticles for neuroprotection by reducing oxidative stress and modulating inflammatory microenvironment in acute …

C Li, Z Zhao, Y Luo, T Ning, P Liu, Q Chen… - Advanced …, 2021 - Wiley Online Library
Reperfusion injury is still a major challenge that impedes neuronal survival in ischemic
stroke. However, the current clinical treatments are remained on single pathological …

Multisociety consensus quality improvement revised consensus statement for endovascular therapy of acute ischemic stroke

D Sacks, B Baxter, BCV Campbell… - … journal of stroke, 2018 - journals.sagepub.com
Endovascular therapy (EVT) for acute ischemic stroke in selected patients has recently been
proven effective in several clinical trials, and the widespread adoption of thrombectomy into …

Delays in stroke onset to hospital arrival time during COVID-19

KC Teo, WCY Leung, YK Wong, RKC Liu, AHY Chan… - Stroke, 2020 - Am Heart Assoc
Background and Purpose: The current coronavirus disease 2019 (COVID-19) pandemic
represents a global public health crisis, disrupting emergency healthcare services. We …

Neutrophil extracellular traps in ischemic stroke thrombi

E Laridan, F Denorme, L Desender… - Annals of …, 2017 - Wiley Online Library
Objective Neutrophil extracellular traps (NETs) have been shown to promote thrombus
formation. Little is known about the exact composition of thrombi that cause ischemic stroke …

Disease control priorities: improving health and reducing poverty

DT Jamison - The Lancet, 2018 - thelancet.com
In addition to develo** essential packages some DCP3 volumes identify one or more
“augmented” packages that delineate next steps after the essential interventions are …

Structural analysis of ischemic stroke thrombi: histological indications for therapy resistance

S Staessens, F Denorme, O Francois… - …, 2019 - pmc.ncbi.nlm.nih.gov
Ischemic stroke is caused by a thromboembolic occlusion of cerebral arteries. Treatment is
focused on fast and efficient removal of the occluding thrombus, either via intravenous …