Ultra-high-performance liquid chromatography high-resolution mass spectrometry variants for metabolomics research

L Perez de Souza, S Alseekh, F Scossa, AR Fernie - Nature methods, 2021 - nature.com
Ultra-high-performance liquid chromatography high-resolution mass spectrometry (UHPLC–
HRMS) variants currently represent the best tools to tackle the challenges of complexity and …

A review of NMR analysis in polysaccharide structure and conformation: Progress, challenge and perspective

JQ Wang, JY Yin, SP Nie, MY **e - Food Research International, 2021 - Elsevier
Nuclear magnetic resonance (NMR) has been widely used as an analytical chemistry
technique to investigate the molecular structure and conformation of polysaccharides …

Metabolomic profiles predict individual multidisease outcomes

T Buergel, J Steinfeldt, G Ruyoga, M Pietzner… - Nature medicine, 2022 - nature.com
Risk stratification is critical for the early identification of high-risk individuals and disease
prevention. Here we explored the potential of nuclear magnetic resonance (NMR) …

[HTML][HTML] NMR spectroscopy for metabolomics research

AH Emwas, R Roy, RT McKay, L Tenori, E Saccenti… - Metabolites, 2019 - mdpi.com
Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the
three principal analytical techniques used in metabolomics (the other two being gas …

Spatially resolved mass spectrometry at the single cell: recent innovations in proteomics and metabolomics

MJ Taylor, JK Lukowski… - Journal of the American …, 2021 - ACS Publications
Biological systems are composed of heterogeneous populations of cells that
intercommunicate to form a functional living tissue. Biological function varies greatly across …

[HTML][HTML] NMR and metabolomics—A roadmap for the future

DS Wishart, LL Cheng, V Copié, AS Edison… - Metabolites, 2022 - mdpi.com
Metabolomics investigates global metabolic alterations associated with chemical, biological,
physiological, or pathological processes. These metabolic changes are measured with …

Recent advances in the application of metabolomics for food safety control and food quality analyses

S Li, Y Tian, P Jiang, Y Lin, X Liu… - Critical reviews in food …, 2021 - Taylor & Francis
As one of the omics fields, metabolomics has unique advantages in facilitating the
understanding of physiological and pathological activities in biology, physiology, pathology …

Metabolomics and isotope tracing

C Jang, L Chen, JD Rabinowitz - Cell, 2018 - cell.com
Great strides have been made over the past decade toward comprehensive study of
metabolism. Mass spectrometry (MS) has played a central role by enabling measurement of …

[HTML][HTML] A review of environmental metabolism disrupting chemicals and effect biomarkers associating disease risks: Where exposomics meets metabolomics

J Sun, R Fang, H Wang, DX Xu, J Yang, X Huang… - Environment …, 2022 - Elsevier
Humans are exposed to an ever-increasing number of environmental toxicants, some of
which have gradually been elucidated to be important risk factors for metabolic diseases …

DEEP picker is a deep neural network for accurate deconvolution of complex two-dimensional NMR spectra

DW Li, AL Hansen, C Yuan, L Bruschweiler-Li… - Nature …, 2021 - nature.com
The analysis of nuclear magnetic resonance (NMR) spectra for the comprehensive and
unambiguous identification and characterization of peaks is a difficult, but critically important …