Potential therapeutic and pharmacological effects of Wogonin: an updated review

DL Huynh, TH Ngau, NH Nguyen, GB Tran… - Molecular Biology …, 2020 - Springer
Flavonoids are members of polyphenolic compounds, which are naturally presented in fruits,
vegetables, and some medicinal plants. Traditionally, the root of Scutellaria baicalensis is …

The multifaced role of HtrA1 in the development of joint and skeletal disorders

G Tossetta, S Fantone, C Licini, D Marzioni… - Bone, 2022 - Elsevier
HtrA1 (High temperature requirement A1) family proteins include four members, widely
conserved from prokaryotes to eukaryotes, named HtrA1, HtrA2, HtrA3 and HtrA4. HtrA1 is a …

Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis

X Liu, X Peng, S Cen, C Yang, Z Ma… - Frontiers in Pharmacology, 2023 - frontiersin.org
Pancreatic cancer is a common gastrointestinal tract malignancy. Currently, the therapeutic
strategies for pancreatic cancers include surgery, radiotherapy, and chemotherapy; …

The Use of Chinese Skullcap (Scutellaria baicalensis) and Its Extracts for Sustainable Animal Production

B Yin, W Li, H Qin, J Yun, X Sun - Animals, 2021 - mdpi.com
Simple Summary With the increasing pressure to address the problems of bacterial
resistance and drug residues, medicinal herbs are gradually taking a more important role in …

Experimental therapeutics for the treatment of osteoarthritis

G Schulze-Tanzil - Journal of experimental pharmacology, 2021 - Taylor & Francis
Osteoarthritis (OA) therapy remains a large challenge since no causative treatment options
are so far available. Despite some main pathways contributing to OA are identified its …

Nutraceutical activity in osteoarthritis biology: a focus on the nutrigenomic role

S D'Adamo, S Cetrullo, V Panichi, E Mariani… - Cells, 2020 - mdpi.com
Osteoarthritis (OA) is a disease associated to age or conditions that precipitate aging of
articular cartilage, a post-mitotic tissue that remains functional until the failure of major …

Natural anti‐inflammatory products for osteoarthritis: From molecular mechanism to drug delivery systems and clinical trials

J Su, M Yu, H Wang, Y Wei - Phytotherapy Research, 2023 - Wiley Online Library
Osteoarthritis (OA) is a degenerative joint disease that affects millions globally. The present
nonsteroidal anti‐inflammatory drug treatments have different side effects, leading …

[HTML][HTML] Nutritional epigenomics: bioactive dietary compounds in the epigenetic regulation of osteoarthritis

KM Villagrán-Andrade, C Núñez-Carro, FJ Blanco… - Pharmaceuticals, 2024 - mdpi.com
Nutritional epigenomics is exceptionally important because it describes the complex
interactions among food compounds and epigenome modifications. Phytonutrients or …

Wogonin, a bioactive ingredient from huangqi guizhi formula, alleviates discogenic low back pain via suppressing the overexpressed NGF in intervertebral discs

J Li, W Duan, S Chai, Y Luo, Y Ma… - Mediators of …, 2023 - Wiley Online Library
Purpose. To investigate whether wogonin, a key bioactive ingredient of Huangqi Guizhi
formula (HQGZ formula; a Traditional Chinese Medicine herbal formula) according to …

The combination of molecular docking and network pharmacology reveals the molecular mechanism of Danggui Niantong decoction in treating gout

Y Liu, D Luo, B Xu - Medicine, 2022 - journals.lww.com
Background: Due to unhealthy diet and living habits, the incidence of gout is on the rise and
has become a common disease with a high incidence. Danggui Niantong decoction …