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Copper oxide nanoparticles: In vitro and in vivo toxicity, mechanisms of action and factors influencing their toxicology
Abstract Copper oxide nanoparticles (CuO NPs) have received increasing interest due to
their distinctive properties, including small particle size, high surface area, and reactivity …
their distinctive properties, including small particle size, high surface area, and reactivity …
Systematic review: quantitative susceptibility map** (QSM) of brain iron profile in neurodegenerative diseases
Iron has been increasingly implicated in the pathology of neurodegenerative diseases. In
the past decade, development of the new magnetic resonance imaging technique …
the past decade, development of the new magnetic resonance imaging technique …
Wilson's disease: update on pathogenesis, biomarkers and treatments
S Shribman, A Poujois, O Bandmann… - Journal of Neurology …, 2021 - jnnp.bmj.com
Wilson's disease is an autosomal–recessive disorder of copper metabolism caused by
mutations in ATP7B and associated with neurological, psychiatric, ophthalmological and …
mutations in ATP7B and associated with neurological, psychiatric, ophthalmological and …
[HTML][HTML] Deadly excess copper
J Sailer, J Nagel, B Akdogan, AT Jauch, J Engler… - Redox biology, 2024 - Elsevier
Higher eukaryotes' life is impossible without copper redox activity and, literally, every breath
we take biochemically demonstrates this. However, this dependence comes at a …
we take biochemically demonstrates this. However, this dependence comes at a …
[HTML][HTML] Copper ions and Parkinson's disease: why is homeostasis so relevant?
The involvement of copper in numerous physiological processes makes this metal ion
essential for human life. Alterations in copper homeostasis might have deleterious …
essential for human life. Alterations in copper homeostasis might have deleterious …
A delicate balance: Iron metabolism and diseases of the brain
Iron is the most abundant transition metal within the brain, and is vital for a number of
cellular processes including neurotransmitter synthesis, myelination of neurons, and …
cellular processes including neurotransmitter synthesis, myelination of neurons, and …
The many “faces” of copper in medicine and treatment
Copper (Cu) is an essential microelement found in all living organisms with the unique
ability to adopt two different redox states—in the oxidized (Cu 2+) and reduced (Cu+). It is …
ability to adopt two different redox states—in the oxidized (Cu 2+) and reduced (Cu+). It is …
The neurotoxicity of iron, copper and manganese in Parkinson's and Wilson's diseases
Impaired cellular homeostasis of metals, particularly of Cu, Fe and Mn may trigger
neurodegeneration through various mechanisms, notably induction of oxidative stress …
neurodegeneration through various mechanisms, notably induction of oxidative stress …
[HTML][HTML] The role of zinc in the treatment of Wilson's disease
Wilson's disease (WD) is a hereditary disorder of copper metabolism, producing abnormally
high levels of non-ceruloplasmin-bound copper, the determinant of the pathogenic process …
high levels of non-ceruloplasmin-bound copper, the determinant of the pathogenic process …
Extracellular Cu2+ pools and their detection: From current knowledge to next-generation probes
Copper (Cu) is an essential micronutrient for most organisms and serves mainly as a redox-
active catalytic centre in enzymes cycling between Cu+ and Cu 2+. Membrane transporters …
active catalytic centre in enzymes cycling between Cu+ and Cu 2+. Membrane transporters …