Aneuploidy, a genomic alternation characterized by deviations in the copy number of
chromosomes, affects organisms from early development through to aging. Although it is a …

Aneuploidy, chromosome stoichiometry that deviates from exact multiples of the haploid
compliment of an organism, exists in eukaryotic microbes, several normal human tissues …

Leishmania infections span a range of clinical syndromes and impact humans from many
geographic foci, but primarily the world's poorest regions. Transmitted by the bite of a female …

Aneuploidy is widely observed in both unicellular and multicellular eukaryotes, usually
associated with adaptation to stress conditions. Chromosomal duplication stability is a …

Protozoan parasites of the Leishmania donovani complex–L. donovani and L. infantum–
cause the fatal disease visceral leishmaniasis. We present the first comprehensive genome …

Aneuploidy is the loss or gain of chromosomes within a genome. It is often detrimental and
has been associated with cell death and genetic disorders. However, aneuploidy can also …

Protozoan parasites of the genus Leishmania adapt to environmental change through
chromosome and gene copy number variations. Only little is known about external or …

Abstract Treatment failure (TF) jeopardizes the management of parasitic diseases, including
leishmaniasis. From the parasite's point of view, drug resistance (DR) is generally …

Hybrid genotypes have been repeatedly described among natural isolates of Leishmania,
and the recovery of experimental hybrids from sand flies co-infected with different strains or …

For a long time Leishmaniasis had been considered as a neglected tropical disease.
Recently, it has become a priority in public health all over the world for different aspects such …