Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments
Z Yuan, Y Li, S Zhang, X Wang, H Dou, X Yu, Z Zhang… - Molecular cancer, 2023 - Springer
The malignant tumor is a multi-etiological, systemic and complex disease characterized by
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …
uncontrolled cell proliferation and distant metastasis. Anticancer treatments including …
Extracellular matrix and its therapeutic potential for cancer treatment
J Huang, L Zhang, D Wan, L Zhou, S Zheng… - … and Targeted Therapy, 2021 - nature.com
The extracellular matrix (ECM) is one of the major components of tumors that plays multiple
crucial roles, including mechanical support, modulation of the microenvironment, and a …
crucial roles, including mechanical support, modulation of the microenvironment, and a …
CD44 as a tumor biomarker and therapeutic target
H Xu, M Niu, X Yuan, K Wu, A Liu - Experimental hematology & oncology, 2020 - Springer
CD44, a complex transmembrane glycoprotein, exists in multiple molecular forms, including
the standard isoform CD44s and CD44 variant isoforms. CD44 participates in multiple …
the standard isoform CD44s and CD44 variant isoforms. CD44 participates in multiple …
[HTML][HTML] Hyaluronic acid and its biomedical applications: A review
M Dovedytis, ZJ Liu, S Bartlett - Engineered Regeneration, 2020 - Elsevier
Hyaluronic acid is a naturally occurring biopolymer possessing numerous functions within
the body including wound repair, cell migration, and cell signaling. Due to its versatility …
the body including wound repair, cell migration, and cell signaling. Due to its versatility …
[HTML][HTML] Recent advances in polysaccharides based biomaterials for drug delivery and tissue engineering applications
In this paper, a spotlight is shown on polysaccharides based biomaterials which have
surfaced as a versatile platform for different biomedical applications including drug delivery …
surfaced as a versatile platform for different biomedical applications including drug delivery …
The role of CD44 in pathological angiogenesis
L Chen, C Fu, Q Zhang, C He, F Zhang… - The FASEB …, 2020 - Wiley Online Library
Angiogenesis is required for normal development and occurs as a pathological step in a
variety of disease settings, such as cancer, ocular diseases, and ischemia. Recent studies …
variety of disease settings, such as cancer, ocular diseases, and ischemia. Recent studies …
Hyaluronan receptors as mediators and modulators of the tumor microenvironment
The tumor microenvironment (TME) is a dynamic and complex matter shaped by
heterogenous cancer and cancer‐associated cells present at the tumor site. Hyaluronan …
heterogenous cancer and cancer‐associated cells present at the tumor site. Hyaluronan …
A focused review on hyaluronic acid contained nanofiber formulations for diabetic wound healing
The significant clinical challenge presented by diabetic wounds is due to their impaired
healing process and increased risk of complications. It is estimated that a foot ulcer will …
healing process and increased risk of complications. It is estimated that a foot ulcer will …
Chitosan–hyaluronic acid nanoparticles for active targeting in cancer therapy
Cancer is the most common cause of death worldwide; therefore, there is a need to discover
novel treatment modalities to combat it. One of the cancer treatments is nanoparticle …
novel treatment modalities to combat it. One of the cancer treatments is nanoparticle …
Multiple aspects of matrix stiffness in cancer progression
A Mancini, MT Gentile, F Pentimalli… - Frontiers in …, 2024 - pmc.ncbi.nlm.nih.gov
The biophysical and biomechanical properties of the extracellular matrix (ECM) are crucial
in the processes of cell differentiation and proliferation. However, it is unclear to what extent …
in the processes of cell differentiation and proliferation. However, it is unclear to what extent …