Drug addiction is a worldwide societal problem and public health burden, and results from
recreational drug use that develops into a complex brain disorder. The opioid system, one of …

Abstract Purpose of Review With the advent of the genome-wide association study (GWAS),
our understanding of the genetics of addiction has made significant strides forward. Here …

Attributes of alcohol sensitivity are present before alcohol use disorders (AUD s) develop,
they predict those adverse alcohol outcomes, are familial in nature, and many are heritable …

Aims This study used a behavioral approach‐avoidance task including images of alcoholic
beverages to test whether low sensitivity to alcohol (LS) is a phenotypical marker of a …

Background and aims In susceptible individuals, cues associated with drug use are
theorized to take on incentive–motivational properties, including the ability to reinforce …

This paper is the fortieth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Early life stress, specifically childhood maltreatment, and parental risk for mood and
substance use disorders (SUDs) are associated with increased risk for alcohol use disorder …

Background Genetic variation in the endogenous opioid system has been identified as 1
potential source of individual variability in naltrexone treatment outcomes. The majority of …

Introduction Alcohol is among the most commonly used psychoactive drugs, yet it can
produce markedly different subjective effects in different people. Certain effects, including …

Abstract Purpose of Review The present review provides a summary of the progress that
genome-wide association studies (GWAS) have made in identifying the genetic variants that …