Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial
socioeconomic implications for patients and their care-givers. Recent advances in medical …

Stroke is the second most common cause of death and the leading cause of disability
worldwide. Brain injury following stroke results from a complex series of pathophysiological …

Sepsis, characterized by immoderate production of multiple reactive oxygen and nitrogen
species (RONS), causes high morbidity and mortality. Despite progress made with …

Ergothioneine (ERG) is an unusual thio-histidine betaine amino acid that has potent
antioxidant activities. It is synthesised by a variety of microbes, especially fungi (including in …

Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Simple Summary Chronic stress and inflammation, known also as “secret killers” in animals,
can lead to lipid peroxidation, protein oxidation and nitration, DNA damage, and finally …

The pathophysiology of acute spinal cord injury (SCI) involves primary and secondary
mechanisms of injury. Though both mechanisms are involved in the neurological …

The discovery that mammalian cells have the ability to synthesize the free radical nitric oxide
(NO) has stimulated an extraordinary impetus for scientific research in all the fields of …

Superoxide dismutase (SOD) is a common antioxidant enzyme found majorly in living cells.
The main physiological role of SOD is detoxification and maintain the redox balance, acts as …

Reactive oxygen species (ROS) are a chemical class of molecules that have generally been
conceptualized as deleterious entities, albeit ones whose destructive properties could be …