Nanoparticle diffusion in respiratory mucus influenced by mucociliary clearance: a review of mathematical modeling

MH Sedaghat, M Behnia, O Abouali - Journal of Aerosol Medicine …, 2023 - liebertpub.com
Background: Inhalation and deposition of particles in human airways have attracted
considerable attention due to importance of particulate pollutants, transmission of infectious …

Goblet cell interactions reorient bundled mucus strands for efficient airway clearance

MF Bos, A Ermund, GC Hansson, J de Graaf - PNAS nexus, 2023 - academic.oup.com
The respiratory tract of larger animals is cleared by swee** bundled strands along the
airway surface. These bundled strands can be millimetric in length and consist of MUC5B …

On the role of viscoelasticity in mucociliary clearance: a hydrodynamic continuum approach

A Choudhury, M Filoche, NM Ribe… - Journal of Fluid …, 2023 - cambridge.org
We present numerical and analytical predictions of mucociliary clearance based on the
continuum description of a viscoelastic mucus film, where momentum transfer from the …

[HTML][HTML] Three-dimensional simulation of mucociliary clearance under the ciliary abnormalities

MH Sedaghat, S Sadrizadeh, O Abouali - Journal of Non-Newtonian Fluid …, 2023 - Elsevier
In this study three-dimensional computational model of a segment of bronchial airway
surface liquid has been investigated to study the effect of various cilia abnormalities on …

Insights into the fluid dynamics of bioaerosol formation in a model respiratory tract

S Saha, MK Manna, A Chakravarty, S Sarkar… - …, 2024 - pubs.aip.org
Bioaerosols produced within the respiratory system play an important role in respiratory
disease transmission. These include infectious diseases such as common cold, influenza …

Effects of continuous and discrete boundary conditions on the movement of upper-convected maxwell and Newtonian mucus layers in coughing and sneezing

MA Modaresi, E Shirani - The European Physical Journal Plus, 2022 - epjplus.epj.org
Mucociliary clearance is an important phenomenon inside the respiratory system as a first
defensive mechanism against pathogens. Therefore, any assumption considered for the …

Hydrodynamic coupling of a cilia–mucus system in Herschel–Bulkley flows

Q Mao, U d'Ortona, J Favier - Journal of Fluid Mechanics, 2024 - cambridge.org
The yield stress and shear thinning properties of mucus are identified as critical for ciliary
coordination and mucus transport in human airways. We use here numerical simulations to …

[CITATION][C] Turning through disorder: Models of bundled mucus strands and microswimmers

MF Bos - 2024 - Utrecht University