The modulation of the intestinal microbiota by high-fat diet (HFD) has a major impact on both
immunological and metabolic functions of the host. Taking this into consideration, the aim of …

Alcohol is inextricably linked with the digestive system. It is absorbed through the gut and
metabolised by hepatocytes within the liver. Excessive alcohol use results in alterations to …

Phascolarctobacterium can produce short-chain fatty acids, including acetate and
propionate, and can be associated with the metabolic state and mood of the host. The …

Childhood obesity has reached epidemic levels, representing one of the most serious public
health concerns associated with metabolic syndrome and non-alcoholic fatty liver disease …

This study was aimed at characterizing the gut microbiota (GM) and its functional profile in
two groups of Sardinian subjects with a long healthy life expectancy, overall named Long …

Objective Metformin modifies the gut microbiome in type 2 diabetes and gastrointestinal
tolerance to metformin could be mediated by the gut microbiome. Methods We enrolled 35 …

Pediatric obesity and nonalcoholic steatohepatitis (NASH) are on the rise in industrialized
countries, yet our ability to mechanistically examine this relationship is limited by the lack of …

Background A westernized diet comprising a high caloric intake from animal fats is known to
influence the development of pathological inflammatory conditions. However, there has …

Non‐alcoholic fatty liver disease (NAFLD) is one of the most prevalent metabolic disorders
worldwide, along with obesity and type 2 diabetes. NAFLD involves a series of liver …

Horses are large non-ruminant herbivores and rely on microbial fermentation for energy,
with more than half of their maintenance energy requirement coming from microbial …