[HTML][HTML] The importance of breast adipose tissue in breast cancer

C Kothari, C Diorio, F Durocher - International journal of molecular …, 2020 - mdpi.com
Adipose tissue is a complex endocrine organ, with a role in obesity and cancer. Adipose
tissue is generally linked to excessive body fat, and it is well known that the female breast is …

Pink adipocytes

S Cinti - Trends in Endocrinology & Metabolism, 2018 - cell.com
Adipocytes are lipid-rich parenchymal cells contained in a very plastic organ, whose
composition can undergo striking physiologic changes. In standard conditions the organ …

[HTML][HTML] Microbiota depletion impairs thermogenesis of brown adipose tissue and browning of white adipose tissue

B Li, L Li, M Li, SM Lam, G Wang, Y Wu, H Zhang… - Cell Reports, 2019 - cell.com
The relation between gut microbiota and the host has been suggested to benefit metabolic
homeostasis. Brown adipose tissue (BAT) and beige adipocytes facilitate thermogenesis to …

Adipocyte IRE1α promotes PGC1α mRNA decay and restrains adaptive thermogenesis

Y Chen, Z Wu, S Huang, X Wang, S He, L Liu, Y Hu… - Nature …, 2022 - nature.com
Adipose tissue undergoes thermogenic remodeling in response to thermal stress and
metabolic cues, playing a crucial role in regulating energy expenditure and metabolic …

METTL3 is essential for postnatal development of brown adipose tissue and energy expenditure in mice

Y Wang, M Gao, F Zhu, X Li, Y Yang, Q Yan… - Nature …, 2020 - nature.com
Brown adipose tissue (BAT) undergoes rapid postnatal development and then protects
against cold and obesity into adulthood. However, the molecular mechanism that …

Mammary gland adipocytes in lactation cycle, obesity and breast cancer

G Colleluori, J Perugini, G Barbatelli, S Cinti - Reviews in Endocrine and …, 2021 - Springer
The mammary gland (MG) is an exocrine gland present in female mammals responsible for
the production and secretion of milk during the process of lactation. It is mainly composed by …

[HTML][HTML] Adipose tissue-to-breast cancer crosstalk: Comprehensive insights

Y Wu, X Li, Q Li, C Cheng, L Zheng - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
The review focuses on mechanistic evidence for the link between obesity and breast cancer.
According to the IARC study, there is sufficient evidence that obesity is closely related to a …

Adipose tissue depot differences in adipokines and effects on skeletal and cardiac muscle

A Rodríguez, S Becerril, AW Hernández-Pardos… - Current opinion in …, 2020 - Elsevier
White (WAT) and brown (BAT) adipose tissue communicate with skeletal muscle and heart
through the secretion of adipokines (adiponectin, leptin, omentin, osteopontin or …

The different shades of thermogenic adipose tissue

Y Hu, Y Huang, Y Jiang, L Weng, Z Cai, B He - Current Obesity Reports, 2024 - Springer
Abstract Purpose of Review By providing a concise overview of adipose tissue types,
elucidating the regulation of adipose thermogenic capacity in both physiological contexts …

Switching on the furnace: regulation of heat production in brown adipose tissue

L Li, B Li, M Li, JR Speakman - Molecular aspects of medicine, 2019 - Elsevier
Endothermy requires a source of endogenous heat production. In birds, this is derived
primarily from shivering, but in mammals it is mostly non-shivering thermogenesis (NST) …