Genome-wide association studies in diverse populations
NA Rosenberg, L Huang, EM Jewett… - Nature Reviews …, 2010 - nature.com
Genome-wide association (GWA) studies have identified a large number of SNPs
associated with disease phenotypes. As most GWA studies have been performed in …
associated with disease phenotypes. As most GWA studies have been performed in …
Status of cardiovascular disease and stroke in Hispanics/Latinos in the United States: a science advisory from the American Heart Association
CJ Rodriguez, M Allison, ML Daviglus, CR Isasi… - Circulation, 2014 - Am Heart Assoc
Background and Purpose—This American Heart Association (AHA) scientific statement
provides a comprehensive overview of current evidence on the burden cardiovascular …
provides a comprehensive overview of current evidence on the burden cardiovascular …
Sensitive detection of chromosomal segments of distinct ancestry in admixed populations
AL Price, A Tandon, N Patterson, KC Barnes… - PLoS …, 2009 - journals.plos.org
Identifying the ancestry of chromosomal segments of distinct ancestry has a wide range of
applications from disease map** to learning about history. Most methods require the use …
applications from disease map** to learning about history. Most methods require the use …
Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America
To provide a resource for assessing continental ancestry in a wide variety of genetic studies,
we identified, validated, and characterized a set of 128 ancestry informative markers (AIMs) …
we identified, validated, and characterized a set of 128 ancestry informative markers (AIMs) …
Analysis of genomic diversity in Mexican Mestizo populations to develop genomic medicine in Mexico
Mexico is develo** the basis for genomic medicine to improve healthcare of its population.
The extensive study of genetic diversity and linkage disequilibrium structure of different …
The extensive study of genetic diversity and linkage disequilibrium structure of different …
Geographic patterns of genome admixture in Latin American Mestizos
The large and diverse population of Latin America is potentially a powerful resource for
elucidating the genetic basis of complex traits through admixture map**. However, no …
elucidating the genetic basis of complex traits through admixture map**. However, no …
Variant in PNPLA3 is associated with alcoholic liver disease
C Tian, RP Stokowski, D Kershenobich, DG Ballinger… - Nature …, 2010 - nature.com
Two genome-wide association studies (GWAS) have described associations of variants in
PNPLA3 with nonalcoholic fatty liver and plasma liver enzyme levels. We investigated the …
PNPLA3 with nonalcoholic fatty liver and plasma liver enzyme levels. We investigated the …
Estimating local ancestry in admixed populations
S Sankararaman, S Sridhar, G Kimmel… - The American Journal of …, 2008 - cell.com
Large-scale genoty** of SNPs has shown a great promise in identifying markers that
could be linked to diseases. One of the major obstacles involved in performing these studies …
could be linked to diseases. One of the major obstacles involved in performing these studies …
Development of a panel of genome-wide ancestry informative markers to study admixture throughout the Americas
Most individuals throughout the Americas are admixed descendants of Native American,
European, and African ancestors. Complex historical factors have resulted in varying …
European, and African ancestors. Complex historical factors have resulted in varying …
Interethnic admixture and the evolution of Latin American populations
FM Salzano, M Sans - Genetics and molecular biology, 2014 - SciELO Brasil
A general introduction to the origins and history of Latin American populations is followed by
a systematic review of the data from molecular autosomal assessments of the …
a systematic review of the data from molecular autosomal assessments of the …