MicroRNAs in infectious diseases: potential diagnostic biomarkers and therapeutic targets

M Kimura, S Kothari, W Gohir… - Clinical microbiology …, 2023 - journals.asm.org
MicroRNAs (miRNAs) are conserved, short, non-coding RNAs that play a crucial role in the
post-transcriptional regulation of gene expression. They have been implicated in the …

Sexual development in Plasmodium parasites: knowing when it's time to commit

GA Josling, M Llinás - Nature Reviews Microbiology, 2015 - nature.com
Malaria is a devastating infectious disease that is caused by blood-borne apicomplexan
parasites of the genus Plasmodium. These pathogens have a complex lifecycle, which …

[KNIHA][B] Evolutionary parasitology: the integrated study of infections, immunology, ecology, and genetics

P Schmid-Hempel - 2021 - books.google.com
Parasites and infectious diseases are everywhere and represent some of the most potent
forces sha** the natural world. They affect almost every aspect imaginable in the life of …

Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination

T Bousema, C Drakeley - Clinical microbiology reviews, 2011 - journals.asm.org
Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …

Integrated transcriptomic and proteomic analyses of P. falciparum gametocytes: molecular insight into sex-specific processes and translational repression

E Lasonder, SR Rijpma, BCL van Schaijk… - Nucleic acids …, 2016 - academic.oup.com
Sexual differentiation of malaria parasites into gametocytes in the vertebrate host and
subsequent gamete fertilization in mosquitoes is essential for the spreading of the disease …

PlasmoDB: a functional genomic database for malaria parasites

C Aurrecoechea, J Brestelli, BP Brunk… - Nucleic acids …, 2009 - academic.oup.com
Abstract PlasmoDB (http://PlasmoDB. org) is a functional genomic database for Plasmodium
spp. that provides a resource for data analysis and visualization in a gene-by-gene or …

Graph clustering via a discrete uncoupling process

S Van Dongen - SIAM Journal on Matrix Analysis and Applications, 2008 - SIAM
A discrete uncoupling process for finite spaces is introduced, called the Markov Cluster
Process or the MCL process. The process is the engine for the graph clustering algorithm …

Comparative genomics of the neglected human malaria parasite Plasmodium vivax

JM Carlton, JH Adams, JC Silva, SL Bidwell, H Lorenzi… - Nature, 2008 - nature.com
The human malaria parasite Plasmodium vivax is responsible for 25–40% of the∼ 515
million annual cases of malaria worldwide. Although seldom fatal, the parasite elicits severe …

Single-cell RNA-seq reveals hidden transcriptional variation in malaria parasites

AJ Reid, AM Talman, HM Bennett, AR Gomes… - elife, 2018 - elifesciences.org
Single-cell RNA-sequencing is revolutionising our understanding of seemingly
homogeneous cell populations but has not yet been widely applied to single-celled …

A comprehensive evaluation of rodent malaria parasite genomes and gene expression

TD Otto, U Böhme, AP Jackson, M Hunt… - BMC biology, 2014 - Springer
Background Rodent malaria parasites (RMP) are used extensively as models of human
malaria. Draft RMP genomes have been published for Plasmodium yoelii, P. berghei ANKA …