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Hippocampal sharp wave‐ripple: A cognitive biomarker for episodic memory and planning
G Buzsáki - Hippocampus, 2015 - Wiley Online Library
Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …
mammalian brain. Their excitatory output affects a wide area of the cortex and several …
Hippocampal GABAergic inhibitory interneurons
KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …
of the total neuronal population; however, their remarkable anatomical and physiological …
How development sculpts hippocampal circuits and function
R Cossart, R Khazipov - Physiological Reviews, 2022 - journals.physiology.org
In mammals, the selective transformation of transient experience into stored memory occurs
in the hippocampus, which develops representations of specific events in the context in …
in the hippocampus, which develops representations of specific events in the context in …
The interneuron energy hypothesis: implications for brain disease
O Kann - Neurobiology of disease, 2016 - Elsevier
Fast-spiking, inhibitory interneurons–prototype is the parvalbumin-positive (PV+) basket cell–
generate action potentials at high frequency and synchronize the activity of numerous …
generate action potentials at high frequency and synchronize the activity of numerous …
Mechanisms of sharp wave initiation and ripple generation
Replay of neuronal activity during hippocampal sharp wave-ripples (SWRs) is essential in
memory formation. To understand the mechanisms underlying the initiation of irregularly …
memory formation. To understand the mechanisms underlying the initiation of irregularly …
The ketogenic diet: metabolic influences on brain excitability and epilepsy
A dietary therapy for pediatric epilepsy known as the ketogenic diet has seen a revival in its
clinical use during the past decade. Although the underlying mechanism of the diet remains …
clinical use during the past decade. Although the underlying mechanism of the diet remains …
[HTML][HTML] Pathway-specific feedforward circuits between thalamus and neocortex revealed by selective optical stimulation of axons
Thalamocortical and corticothalamic pathways mediate bidirectional communication
between the thalamus and neocortex. These pathways are entwined, making their study …
between the thalamus and neocortex. These pathways are entwined, making their study …
Highly energized inhibitory interneurons are a central element for information processing in cortical networks
Gamma oscillations (~ 30 to 100 Hz) provide a fundamental mechanism of information
processing during sensory perception, motor behavior, and memory formation by …
processing during sensory perception, motor behavior, and memory formation by …
Excitatory effects of parvalbumin-expressing interneurons maintain hippocampal epileptiform activity via synchronous afterdischarges
Epileptic seizures are characterized by periods of hypersynchronous, hyperexcitability within
brain networks. Most seizures involve two stages: an initial tonic phase, followed by a longer …
brain networks. Most seizures involve two stages: an initial tonic phase, followed by a longer …
Parvalbumin-containing fast-spiking basket cells generate the field potential oscillations induced by cholinergic receptor activation in the hippocampus
Gamma frequency oscillations in cortical regions can be recorded during cognitive
processes, including attention or memory tasks. These oscillations are generated locally as …
processes, including attention or memory tasks. These oscillations are generated locally as …