Hippocampal sharp wave‐ripple: A cognitive biomarker for episodic memory and planning

G Buzsáki - Hippocampus, 2015 - Wiley Online Library
Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …

Hippocampal GABAergic inhibitory interneurons

KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

How development sculpts hippocampal circuits and function

R Cossart, R Khazipov - Physiological Reviews, 2022 - journals.physiology.org
In mammals, the selective transformation of transient experience into stored memory occurs
in the hippocampus, which develops representations of specific events in the context in …

The interneuron energy hypothesis: implications for brain disease

O Kann - Neurobiology of disease, 2016 - Elsevier
Fast-spiking, inhibitory interneurons–prototype is the parvalbumin-positive (PV+) basket cell–
generate action potentials at high frequency and synchronize the activity of numerous …

Mechanisms of sharp wave initiation and ripple generation

D Schlingloff, S Káli, TF Freund, N Hájos… - Journal of …, 2014 - jneurosci.org
Replay of neuronal activity during hippocampal sharp wave-ripples (SWRs) is essential in
memory formation. To understand the mechanisms underlying the initiation of irregularly …

The ketogenic diet: metabolic influences on brain excitability and epilepsy

A Lutas, G Yellen - Trends in neurosciences, 2013 - cell.com
A dietary therapy for pediatric epilepsy known as the ketogenic diet has seen a revival in its
clinical use during the past decade. Although the underlying mechanism of the diet remains …

Highly energized inhibitory interneurons are a central element for information processing in cortical networks

O Kann, IE Papageorgiou… - Journal of Cerebral …, 2014 - journals.sagepub.com
Gamma oscillations (~ 30 to 100 Hz) provide a fundamental mechanism of information
processing during sensory perception, motor behavior, and memory formation by …

Pathway-specific feedforward circuits between thalamus and neocortex revealed by selective optical stimulation of axons

SJ Cruikshank, H Urabe, AV Nurmikko, BW Connors - Neuron, 2010 - cell.com
Thalamocortical and corticothalamic pathways mediate bidirectional communication
between the thalamus and neocortex. These pathways are entwined, making their study …

Lactate as a supplemental fuel for synaptic transmission and neuronal network oscillations: Potentials and limitations

O Kann - Journal of neurochemistry, 2024 - Wiley Online Library
Lactate shuttled from the blood circulation, astrocytes, oligodendrocytes or even activated
microglia (resident macrophages) to neurons has been hypothesized to represent a major …

Co-transmission of acetylcholine and GABA regulates hippocampal states

VT Takács, C Cserép, D Schlingloff, B Pósfai… - Nature …, 2018 - nature.com
The basal forebrain cholinergic system is widely assumed to control cortical functions via
non-synaptic transmission of a single neurotransmitter. Yet, we find that mouse hippocampal …