Abstract Microbial Whole-Cell Biosensors (MWCBs) have seen rapid development with the
arrival of 21st century biological and technological capabilities. They consist of microbial …

Synthetic biology has promoted the development of biosensors as tools for detecting trace
substances. In the past, biosensors based on synthetic biology have been designed on …

Advances in synthetic biology and genetic engineering are bringing into the spotlight a wide
range of bio-based applications that demand better sensing and control of biological …

Cadmium poses a severe health risk, impacting various bodily systems. Monitoring human
exposure is vital. Urine and blood cadmium serve as critical biomarkers. However, current …

Mercury contamination in the environment has reached alarming levels. Due to its
persistence and bioaccumulation, mercury is one of the most widespread toxic heavy metals …

Cell-free gene expression (CFE) systems empower synthetic biologists to build biological
molecules and processes outside of living intact cells. The foundational principle is that …

Food safety has always been a hot issue of social concern, and biosensing has been widely
used in the field of food safety detection. Compared with traditional aptamer‐based …

Owning to the elimination of deficiencies in cell survival, cell membrane limitation, and long
response time, biosensors based on cell-free synthetic expression (CFSE) exhibit high …

Synthetic biology aims to engineer biological systems for customized tasks through the
bottom-up assembly of fundamental building blocks, which requires high-quality libraries of …

Whole-cell biosensors could be helpful for in situ disease diagnosis. However, their use in
analyzing biological samples has been hindered by unstable responses, low signal …