Formulation strategy and use of excipients in pulmonary drug delivery
G Pilcer, K Amighi - International journal of pharmaceutics, 2010 - Elsevier
Pulmonary administration of drugs presents several advantages in the treatment of many
diseases. Considering local and systemic delivery, drug inhalation enables a rapid and …
diseases. Considering local and systemic delivery, drug inhalation enables a rapid and …
[HTML][HTML] Technological and practical challenges of dry powder inhalers and formulations
M Hoppentocht, P Hagedoorn, HW Frijlink… - Advanced drug delivery …, 2014 - Elsevier
In the 50 years following the introduction of the first dry powder inhaler to the market, several
developments have occurred. Multiple-unit dose and multi-dose devices have been …
developments have occurred. Multiple-unit dose and multi-dose devices have been …
Pulmonary drug delivery strategies: A concise, systematic review
JS Patil, S Sarasija - Lung India, 2012 - journals.lww.com
Because of limitations associated with the conventional treatment of various chronic
diseases a growing attention has been given to the development of targeted drug delivery …
diseases a growing attention has been given to the development of targeted drug delivery …
Dry powder inhalers (DPIs)—a review of device reliability and innovation
N Islam, E Gladki - International journal of pharmaceutics, 2008 - Elsevier
A wide range of dry powder inhaler (DPI) devices are currently available on the market to
deliver drugs into lungs with a view to maximise drug delivery with low variability. DPIs also …
deliver drugs into lungs with a view to maximise drug delivery with low variability. DPIs also …
Pulmonary drug delivery by powder aerosols
MY Yang, JGY Chan, HK Chan - Journal of Controlled Release, 2014 - Elsevier
The efficacy of pharmaceutical aerosols relates to its deposition in the clinically relevant
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …
regions of the lungs, which can be assessed by in vivo lung deposition studies. Dry powder …
Emerging inhalation aerosol devices and strategies: where are we headed?
Novel inhaled therapeutics including antibiotics, vaccines and anti-hypertensives, have led
to innovations in designing suitable delivery systems. These emerging design technologies …
to innovations in designing suitable delivery systems. These emerging design technologies …
Lactose characteristics and the generation of the aerosol
The delivery efficiency of dry-powder products for inhalation is dependent upon the drug
formulation, the inhaler device, and the inhalation technique. Dry powder formulations are …
formulation, the inhaler device, and the inhalation technique. Dry powder formulations are …
[LLIBRE][B] Computational fluid and particle dynamics in the human respiratory system
Traditional research methodologies in the human respiratory system have always been
challenging due to their invasive nature. Recent advances in medical imaging and …
challenging due to their invasive nature. Recent advances in medical imaging and …
Develo** an efficient and reliable dry powder inhaler for pulmonary drug delivery–a review for multidisciplinary researchers
Pulmonary drug delivery is the focus of much research and development because of its
great potential to produce maximum therapeutic benefit. Among the available options the dry …
great potential to produce maximum therapeutic benefit. Among the available options the dry …
In silico models of aerosol delivery to the respiratory tract—development and applications
This review discusses the application of computational models to simulate the transport and
deposition of inhaled pharmaceutical aerosols from the site of particle or droplet formation to …
deposition of inhaled pharmaceutical aerosols from the site of particle or droplet formation to …