Brain aging is a complex process that includes atrophy, vascular injury, and a variety of age-
associated neurodegenerative pathologies, together determining an individual's course of …

Magnetic resonance spectroscopy (MRS) holds promise for understanding neurochemical
mechanisms associated with human cognitive aging in vivo. Recent advances in magnetic …

Brain aging process is influenced by various lifestyle, environmental and genetic factors, as
well as by age-related and often coexisting pathologies. Magnetic resonance imaging and …

As medical imaging enters its information era and presents rapidly increasing needs for big
data analytics, robust pooling and harmonization of imaging data across diverse cohorts …

Introduction Relationships between brain atrophy patterns of typical aging and Alzheimer's
disease (AD), white matter disease, cognition, and AD neuropathology were investigated via …

The concept of brain maintenance refers to the preservation of brain integrity in older age,
while cognitive reserve refers to the capacity to maintain cognition in the presence of …

Brain age is becoming a widely applied imaging-based biomarker of neural aging and
potential proxy for brain integrity and health. We estimated multimodal and modality-specific …

Background and Objective There is a lack of consensus on how to optimally define and
measure resistance and resilience in brain and cognitive aging. Residual methods use …

Pregnancy involves maternal brain adaptations, but little is known about how parity
influences women's brain aging trajectories later in life. In this study, we replicated previous …

Background Cerebral small vessel disease (CSVD) is a common neurological disease
present in the ageing population that is associated with an increased risk of dementia and …