Neutrophils have traditionally been thought of as simple foot soldiers of the innate immune
system with a restricted set of pro-inflammatory functions. More recently, it has become …

Tissue-resident macrophages are a heterogeneous population of immune cells that fulfill
tissue-specific and niche-specific functions. These range from dedicated homeostatic …

Long recognized as an evolutionarily ancient cell type involved in tissue homeostasis and
immune defense against pathogens, macrophages are being rediscovered as regulators of …

Polymorphonuclear leukocytes or neutrophils play a critical role in the maintenance of
intestinal homeostasis. They have elegant defense mechanisms to eliminate microbes that …

Neutrophils, monocytes and macrophages are closely related phagocytic cells that
cooperate during the onset, progression and resolution of inflammation. This Review …

Sepsis causes over 200,000 deaths yearly in the US; better treatments are urgently needed.
Administering bone marrow stromal cells (BMSCs—also known as mesenchymal stem cells) …

Responding to tissue injury, skeletal muscles undergo the tissue destruction and
reconstruction accompanied with inflammation. The immune system recognizes the …

Rapid neutrophil recruitment to sites of inflammation is crucial for innate immune responses.
Here, we reveal that the G-protein-coupled receptor GPR35 is upregulated in activated …

Morbidity and mortality have declined only modestly in patients with clinical acute lung injury
(ALI) and acute respiratory distress syndrome (ARDS), despite extensive research into the …

Background Bone-marrow derived mesenchymal stem cells (MSCs) reduce the severity of
evolving acute lung injury (ALI), but their ability to repair the injured lung is not clear. A study …