Recent progress on engineered micro/nanomaterials mediated modulation of gut microbiota for treating inflammatory bowel disease

L Kan, Z Zheng, W Fu, Y Ma, W Wang, H Qian… - Journal of Controlled …, 2024 - Elsevier
Inflammatory bowel disease (IBD) is a type of chronic recurrent inflammation disease that
mainly includes Crohn's disease and ulcerative colitis. Currently, the treatments for IBD …

Functional chitosan and its derivative-related drug delivery systems for nano-therapy: Recent advances

Z Wang, F Yu, F Hu - Pharmaceutics, 2024 - mdpi.com
In the struggle against diseases, the development of nano-therapy has certainly been a
tremendous progression owing to the various superiority, and chitosan is no doubt a kind of …

Inhibiting the cGAS-STING pathway in ulcerative colitis with programmable micelles

S Uthaman, S Parvinroo, AP Mathew, X Jia… - ACS …, 2024 - ACS Publications
Ulcerative colitis is a chronic condition in which a dysregulated immune response
contributes to the acute intestinal inflammation of the colon. Current clinical therapies often …

Mucoadhesive mesalamine prodrug nanoassemblies to target intestinal macrophages for the treatment of inflammatory bowel disease

B Park, G Han, DY **, KC Gil, D Shin, J Lee, JY Park… - ACS …, 2024 - ACS Publications
While mesalamine, a 5-aminosalicylic acid (5-ASA), is pivotal in the management of
inflammatory bowel disease (IBD) through both step-up and top-down approaches in clinical …

Targeted modulation of intestinal epithelial regeneration and immune response in ulcerative colitis using dual-targeting bilirubin nanoparticles

Z Zhuo, K Guo, Y Luo, Q Yang, H Wu, R Zeng… - …, 2024 - pmc.ncbi.nlm.nih.gov
Rationale: The therapeutic benefits of bilirubin in the treatment of ulcerative colitis (UC) are
considerable, whereas the underlying mechanism of bilirubin on UC remains unclear …

Inflammation, dopaminergic brain and bilirubin

S Jayanti, C Dalla Verde, C Tiribelli… - International Journal of …, 2023 - mdpi.com
Dopamine is a well-known neurotransmitter due to its involvement in Parkinson's disease
(PD). Dopamine is not only involved in PD but also controls multiple mental and physical …

Opening the doors of precision medicine: novel tools to assess intestinal barrier in inflammatory bowel disease and colitis-associated neoplasia

M Iacucci, G Santacroce, S Majumder, J Morael… - Gut, 2024 - gut.bmj.com
Mounting evidence underscores the pivotal role of the intestinal barrier and its convoluted
network with diet and intestinal microbiome in the pathogenesis of inflammatory bowel …

Orally deliverable microalgal-based carrier with selenium nanozymes for alleviation of inflammatory bowel disease

T Chen, X Chi, Y Li, Y Li, R Zhao, L Chen… - … Applied Materials & …, 2024 - ACS Publications
Excessive reactive oxygen species (ROS) is a hallmark of both the onset and progression of
inflammatory bowel disease (IBD), where a continuous cycle of ROS and inflammation …

Intestinal IL-33 promotes microbiota-derived trimethylamine N-oxide synthesis and drives metabolic dysfunction-associated steatotic liver disease progression by …

S Hai, X Li, E **e, W Wu, Q Gao, B Yu, J Hu, F Xu… - Hepatology, 2024 - journals.lww.com
Hepatology Publish Ahead of Print DOI:10.1097/HEP.0000000000000985 Page 1 Intestinal
IL-33 promotes microbiota-derived trimethylamine N-oxide synthesis and drives metabolic …

Fucosylated chondroitin sulfate from sea cucumber Stichopus chloronotus alleviate the intestinal barrier injury and oxidative stress damage in vitro and in vivo

H Yin, R Li, J Liu, Y Sun, L Zhao, J Mou, J Yang - Carbohydrate Polymers, 2024 - Elsevier
This study aimed to investigate the alleviative effects of fucosylated chondroitin sulfate from
sea cucumber Stichopus chloronotus (fCSsingle bond Sc) on the intestinal barrier injury and …