Microfluidic approaches for isolation, detection, and characterization of extracellular vesicles: Current status and future directions
Extracellular vesicles (EVs) are cell-derived vesicles present in body fluids that play an
essential role in various cellular processes, such as intercellular communication …
essential role in various cellular processes, such as intercellular communication …
Phase-change contrast agents for imaging and therapy
PS Sheeran, PA Dayton - Current pharmaceutical design, 2012 - ingentaconnect.com
Phase-change contrast agents (PCCAs) for ultrasound-based applications have resulted in
novel ways of approaching diagnostic and therapeutic techniques beyond what is possible …
novel ways of approaching diagnostic and therapeutic techniques beyond what is possible …
An electric-eel-inspired soft power source from stacked hydrogels
Progress towards the integration of technology into living organisms requires electrical
power sources that are biocompatible, mechanically flexible, and able to harness the …
power sources that are biocompatible, mechanically flexible, and able to harness the …
Design of ultrasonically-activatable nanoparticles using low boiling point perfluorocarbons
PS Sheeran, SH Luois, LB Mullin, TO Matsunaga… - Biomaterials, 2012 - Elsevier
Recently, an interest has developed in designing biomaterials for medical ultrasonics that
can provide the acoustic activity of microbubbles, but with improved stability in vivo and a …
can provide the acoustic activity of microbubbles, but with improved stability in vivo and a …
Nanoparticle‐loaded protein–polymer nanodroplets for improved stability and conversion efficiency in ultrasound imaging and drug delivery
A new formulation of volatile nanodroplets stabilized by a protein and polymer coating and
loaded with magnetic nanoparticles is developed. The droplets show enhanced stability and …
loaded with magnetic nanoparticles is developed. The droplets show enhanced stability and …
Ultrasound‐enhanced siRNA delivery using magnetic nanoparticle‐loaded chitosan‐deoxycholic acid nanodroplets
Small interfering RNA (siRNA) has significant therapeutic potential but its clinical translation
has been severely inhibited by a lack of effective delivery strategies. Previous work has …
has been severely inhibited by a lack of effective delivery strategies. Previous work has …
Controlled release of basic fibroblast growth factor for angiogenesis using acoustically-responsive scaffolds
The clinical translation of pro-angiogenic growth factors for treatment of vascular disease
has remained a challenge due to safety and efficacy concerns. Various approaches have …
has remained a challenge due to safety and efficacy concerns. Various approaches have …
Model of droplet generation in flow focusing generators operating in the squeezing regime
Flow focusing generators have been widely used to generate droplets for many applications
which call for accurate physical models that describe the droplet formation process in such …
which call for accurate physical models that describe the droplet formation process in such …
Phase-transition thresholds and vaporization phenomena for ultrasound phase-change nanoemulsions assessed via high-speed optical microscopy
PS Sheeran, TO Matsunaga… - Physics in Medicine & …, 2013 - iopscience.iop.org
Ultrasonically activated phase-change contrast agents (PCCAs) based on perfluorocarbon
droplets have been proposed for a variety of therapeutic and diagnostic clinical applications …
droplets have been proposed for a variety of therapeutic and diagnostic clinical applications …
Ultrasound-Guided Cytosolic Protein Delivery via Transient Fluorous Masks
The inability to spatiotemporally guide proteins in tissues and efficiently deliver them into
cells remains a key barrier to realizing their full potential in precision medicine. Here, we …
cells remains a key barrier to realizing their full potential in precision medicine. Here, we …