Genetics and epigenetics in obesity
K Rohde, M Keller, L la Cour Poulsen, M Blüher… - Metabolism, 2019 - Elsevier
Obesity is among the most threatening health burdens worldwide and its prevalence has
markedly increased over the last decades. Obesity maybe considered a heritable trait …
markedly increased over the last decades. Obesity maybe considered a heritable trait …
Weight loss and the prevention and treatment of type 2 diabetes using lifestyle therapy, pharmacotherapy, and bariatric surgery: mechanisms of action
J Grams, WT Garvey - Current obesity reports, 2015 - Springer
Weight loss, whether achieved by lifestyle intervention, pharmacotherapy, or bariatric
surgery, is highly effective as a primary interventional strategy in both the prevention and …
surgery, is highly effective as a primary interventional strategy in both the prevention and …
[HTML][HTML] Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients
Objective Epigenetic modifications contribute to the etiology of type 2 diabetes. Method We
performed genome-wide methylome and transcriptome analysis in liver from severely obese …
performed genome-wide methylome and transcriptome analysis in liver from severely obese …
Mouse-human experimental epigenetic analysis unmasks dietary targets and genetic liability for diabetic phenotypes
Using a functional approach to investigate the epigenetics of type 2 diabetes (T2D), we
combine three lines of evidence—diet-induced epigenetic dysregulation in mouse …
combine three lines of evidence—diet-induced epigenetic dysregulation in mouse …
Exercise training alters the genomic response to acute exercise in human adipose tissue
Aim: To determine the genomic mechanisms by which adipose tissue responds to acute and
chronic exercise. Methods: We profiled the transcriptomic and epigenetic response to acute …
chronic exercise. Methods: We profiled the transcriptomic and epigenetic response to acute …
Bariatric surgery-induced weight loss and associated genome-wide DNA-methylation alterations in obese individuals
Background Obesity is a multifactorial and chronic condition of growing universal concern. It
has recently been reported that bariatric surgery is a more successful treatment for severe …
has recently been reported that bariatric surgery is a more successful treatment for severe …
DNA methylation and hydroxymethylation levels in relation to two weight loss strategies: energy-restricted diet or bariatric surgery
Background Weight loss can be influenced by genetic factors and epigenetic mechanisms
that participate in the regulation of body weight. This study aimed to investigate whether the …
that participate in the regulation of body weight. This study aimed to investigate whether the …
Preliminary indications of the effect of a brief yoga intervention on markers of inflammation and DNA methylation in chronically stressed women
Yoga is associated with reduced stress and increased well-being, although the molecular
basis for these benefits is not clear. Mounting evidence implicates the immune response …
basis for these benefits is not clear. Mounting evidence implicates the immune response …
Precision medicine and obesity
A Acosta - Gastroenterology Clinics, 2021 - gastro.theclinics.com
In the last decades, the prevalence of obesity has increased globally, reaching epidemic
proportions. 1 Its worldwide prevalence has almost tripled between 1980 and 2016. 2 In the …
proportions. 1 Its worldwide prevalence has almost tripled between 1980 and 2016. 2 In the …
Obesity-related epigenetic changes after bariatric surgery
Objective: In recent years, an increasing number of studies have begun focusing on
epigenetics as a link between environmental factors and a greater predisposition to the …
epigenetics as a link between environmental factors and a greater predisposition to the …