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Mechanisms and functions of the RNA polymerase II general transcription machinery during the transcription cycle
SR Archuleta, JA Goodrich, JF Kugel - Biomolecules, 2024 - mdpi.com
Central to the development and survival of all organisms is the regulation of gene
expression, which begins with the process of transcription catalyzed by RNA polymerases …
expression, which begins with the process of transcription catalyzed by RNA polymerases …
Disordered C-terminal domain drives spatiotemporal confinement of RNAPII to enhance search for chromatin targets
Efficient gene expression requires RNA polymerase II (RNAPII) to find chromatin targets
precisely in space and time. How RNAPII manages this complex diffusive search in three …
precisely in space and time. How RNAPII manages this complex diffusive search in three …
Defining gene ends: RNA polymerase II CTD threonine 4 phosphorylation marks transcription termination regions genome-wide
M Kopczyńska, U Saha, A Romanenko… - Nucleic Acids …, 2025 - academic.oup.com
Defining the beginning of a eukaryotic protein-coding gene is relatively simple. It
corresponds to the first ribonucleotide incorporated by RNA polymerase II (Pol II) into the …
corresponds to the first ribonucleotide incorporated by RNA polymerase II (Pol II) into the …
Nonspecific interactions in transcription regulation and organization of transcriptional condensates
AA Valyaeva, EV Sheval - Biochemistry (Moscow), 2024 - Springer
Eukaryotic cells are characterized by a high degree of compartmentalization of their internal
contents, which ensures precise and controlled regulation of intracellular processes. During …
contents, which ensures precise and controlled regulation of intracellular processes. During …
Live-cell single-molecule dynamics of eukaryotic RNA polymerase machineries
Eukaryotic gene expression in the nucleus is orchestrated by three RNA polymerases
(RNAP-I,-II, and-III) and associated factors1,. Despite extensive biochemical, genomic …
(RNAP-I,-II, and-III) and associated factors1,. Despite extensive biochemical, genomic …
Topoisomerase regulation in the interplay between DNA transcription and replication
J Grosser - 2024 - openarchive.ki.se
During DNA-involving processes such as transcription and replication the double helix is
subjected to torsional stress. The over-or under-winding that encompasses torsional stress …
subjected to torsional stress. The over-or under-winding that encompasses torsional stress …
RNA 聚合酶 II 大亚基羧基末端结构域: 简单重复不简单
**淇， 董志诚， 刘敏 - 遗传, 2024 - chinagene.cn
转录作为遗传信息传递的关键步骤, 由DNA 依赖的RNA 聚合酶执行. 真核生物中,
蛋白编码基因的转录由RNA 聚合酶II (polymerase II, Pol II) 完成, Pol II 最大亚基RPB1 …
蛋白编码基因的转录由RNA 聚合酶II (polymerase II, Pol II) 完成, Pol II 最大亚基RPB1 …