Numerous neurodegenerative diseases result from altered ion channel function and
mutations. The intracellular redox status can significantly alter the gating characteristics of …

This review focuses on research in epidemiology, neuropathology, molecular biology, and
genetics regarding the hypothesis that pathogens interact with susceptibility genes and are …

Many crowded biomolecular structures in cells and tissues are inaccessible to labelling
antibodies. To understand how proteins within these structures are arranged with nanoscale …

The voltage-gated potassium (Kv) channels, encoded by 40 genes, repolarize all electrically
excitable cells, including plant, cardiac, and neuronal cells. Although these genes were fully …

This review focuses on research in the areas of epidemiology, neuropathology, molecular
biology and genetics that implicates herpes simplex virus type 1 (HSV-1) as a causative …

Advanced identification of the gene mutations causing epilepsy syndromes is expected to
translate into faster diagnosis and more effective treatment of these conditions. Over the last …

Retinal ganglion cells (RGCs), the projection neurons of the eye, cannot regenerate their
axons once the optic nerve has been injured and soon begin to die. Whereas RGC death …

Potassium (K+) channels are expressed in almost every cells and are ubiquitous in neuronal
and glial cell membranes. These channels have been implicated in different disorders, in …

Lactate, a product of aerobic glycolysis in astrocytes, is required for memory formation and
consolidation, and has recently emerged as a signaling molecule for neurons and various …

Traumatic brain injury (TBI), defined as an alteration in brain functions caused by an external
force, is responsible for high morbidity and mortality around the world. It is important to …