Drug repurposing for the treatment of staphylococcal infections
The development and approval of new antimicrobials capable of being used to treat
infections caused by multidrug-resistant pathogens has not kept pace with the rapid …
infections caused by multidrug-resistant pathogens has not kept pace with the rapid …
Identification of Putative Vaccine and Drug Targets against the Methicillin-Resistant Staphylococcus aureus by Reverse Vaccinology and Subtractive Genomics …
Methicillin-resistant Staphylococcus aureus (MRSA) is an opportunistic pathogen and
responsible for causing life-threatening infections. The emergence of hypervirulent and …
responsible for causing life-threatening infections. The emergence of hypervirulent and …
[HTML][HTML] Recent findings related to immune responses against leptospirosis and novel strategies to prevent infection
F Vernel-Pauillac, C Werts - Microbes and Infection, 2018 - Elsevier
What are the new approaches and emerging ideas to prevent leptospirosis, a neglected
bacterial re-emerging zoonotic disease? How do Leptospira interrogans escape the host …
bacterial re-emerging zoonotic disease? How do Leptospira interrogans escape the host …
Identification of potential drug targets by subtractive genome analysis of Escherichia coli O157:H7: an in silico approach
Bacterial enteric infections resulting in diarrhea, dysentery, or enteric fever constitute a huge
public health problem, with more than a billion episodes of disease annually in develo** …
public health problem, with more than a billion episodes of disease annually in develo** …
Inhibitor design against JNK1 through e-pharmacophore modeling docking and molecular dynamics simulations
Abstract c-Jun-NH2 terminal kinases (JNKs) come under a class of serine/threonine protein
kinases and are encoded by three genes, namely JNK1, JNK2 and JNK3. Human JNK1 is a …
kinases and are encoded by three genes, namely JNK1, JNK2 and JNK3. Human JNK1 is a …
[HTML][HTML] In Silico Subtractive Proteomics Approach for Identification of Potential Drug Targets in Staphylococcus saprophyticus
Staphylococcus saprophyticus is a uropathogenic bacteria responsible for acute urinary tract
infections (UTIs) mainly in young female patients. Patients suffering from urinary …
infections (UTIs) mainly in young female patients. Patients suffering from urinary …
Network-Based Metabolism-Centered Screening of Potential Drug Targets in Klebsiella pneumoniae at Genome Scale
Klebsiella pneumoniae is an opportunistic bacterial pathogen leading to life-threatening
nosocomial infections. Emergence of highly resistant strains poses a major challenge in the …
nosocomial infections. Emergence of highly resistant strains poses a major challenge in the …
Comparative Genomics Analysis of Mycobacterium ulcerans for the Identification of Putative Essential Genes and Therapeutic Candidates
Mycobacterium ulcerans, the causative agent of Buruli ulcer, is the third most common
mycobacterial disease after tuberculosis and leprosy. The present treatment options are …
mycobacterial disease after tuberculosis and leprosy. The present treatment options are …
Multi-epitope chimeric vaccine designing and novel drug targets prioritization against multi-drug resistant Staphylococcus pseudintermedius
Biofilm synthesizing multi-drug resistant Staphylococcus pseudintermedius bacteria has
been recognized as the human infectious agent. It has been detected in the diseases of skin …
been recognized as the human infectious agent. It has been detected in the diseases of skin …
Mycoplasma genitalium: a comparative genomics study of metabolic pathways for the identification of drug and vaccine targets
Increasing emergence of antibiotic-resistant pathogenic microorganisms is one of the
biggest challenges for biomedical research and drug development. Traditional drug …
biggest challenges for biomedical research and drug development. Traditional drug …