The interplay between diet and the gut microbiome: implications for health and disease

FC Ross, D Patangia, G Grimaud, A Lavelle… - Nature Reviews …, 2024 - nature.com
Diet has a pivotal role in sha** the composition, function and diversity of the gut
microbiome, with various diets having a profound impact on the stability, functionality and …

Short chain fatty acids: microbial metabolites for gut-brain axis signalling

KJ O'Riordan, MK Collins, GM Moloney… - Molecular and Cellular …, 2022 - Elsevier
The role of the intestinal microbiota as a regulator of gut-brain axis signalling has risen to
prominence in recent years. Understanding the relationship between the gut microbiota, the …

Metagenomics of Parkinson's disease implicates the gut microbiome in multiple disease mechanisms

ZD Wallen, A Demirkan, G Twa, G Cohen… - Nature …, 2022 - nature.com
Parkinson's disease (PD) may start in the gut and spread to the brain. To investigate the role
of gut microbiome, we conducted a large-scale study, at high taxonomic resolution, using …

[HTML][HTML] Brain–gut–microbiota axis in depression: A historical overview and future directions

L Chang, Y Wei, K Hashimoto - Brain Research Bulletin, 2022 - Elsevier
Depression is the most common mental disorder and a leading cause of disability
worldwide. Despite abundant research, the precise mechanisms underlying the …

Short-chain fatty acids in diseases

D Zhang, YP Jian, YN Zhang, Y Li, LT Gu… - Cell Communication and …, 2023 - Springer
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation
of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate …

[HTML][HTML] Exploration of the Muribaculaceae Family in the Gut Microbiota: Diversity, Metabolism, and Function

Y Zhu, B Chen, X Zhang, MT Akbar, T Wu, Y Zhang… - Nutrients, 2024 - mdpi.com
The gut microbiota are mainly composed of Bacteroidetes and Firmicutes and are crucial for
metabolism and immunity. Muribaculaceae are a family of bacteria within the order …

Butyrate-producing Eubacterium rectale suppresses lymphomagenesis by alleviating the TNF-induced TLR4/MyD88/NF-κB axis

H Lu, X Xu, D Fu, Y Gu, R Fan, H Yi, X He, C Wang… - Cell Host & Microbe, 2022 - cell.com
Microbiota-induced tumorigenesis is well established in solid tumors of the gastrointestinal
tract but rarely explored in hematologic malignancies. To determine the role of gut …

Feeding gut microbes to nourish the brain: unravelling the diet–microbiota–gut–brain axis

E Schneider, KJ O'Riordan, G Clarke, JF Cryan - Nature metabolism, 2024 - nature.com
The prevalence of brain disorders, including stress-related neuropsychiatric disorders and
conditions with cognitive dysfunction, is rising. Poor dietary habits contribute substantially to …

Orally administered Odoribacter laneus improves glucose control and inflammatory profile in obese mice by depleting circulating succinate

I Huber-Ruano, E Calvo, J Mayneris-Perxachs… - Microbiome, 2022 - Springer
Background Succinate is produced by both human cells and by gut bacteria and couples
metabolism to inflammation as an extracellular signaling transducer. Circulating succinate is …

Current understanding of the Alzheimer's disease-associated microbiome and therapeutic strategies

D Seo, DM Holtzman - Experimental & molecular medicine, 2024 - nature.com
Alzheimer's disease (AD) is a fatal progressive neurodegenerative disease. Despite
tremendous research efforts to understand this complex disease, the exact pathophysiology …