Sažetak The amorphous form of pharmaceutical materials represents the most energetic
solid state of a material. It provides advantages in terms of dissolution rate and …

Understanding interparticle interactions in powder systems is crucial to pharmaceutical
powder processing. Nevertheless, there remains a great challenge in identifying the key …

Non-isothermal differential scanning calorimetry (DSC) was used to study the influences of
particle size (daver) and heating rate (q+) on the structural relaxation, crystal growth and …

Common energy-intensive processes applied in oral solid dosage development, such as
milling, sieving, blending, compaction, etc. generate particles with surface and bulk crystal …

Differential scanning calorimetry and Raman spectroscopy were used to study the
nonisothermal and isothermal crystallization behavior of amorphous indomethacin powders …

The goal of this study was to provide a better framework for understanding the bulk and
surface disorder in milled crystalline materials. The surface and bulk properties of two model …

Surface composition plays an important role in the cohesion/adhesion behavior of powders.
Yet, the quantification of the major factors that affect powder kinematics is a challenge …

The effect of milling on the transitions of sulfathiazole polymorphs in the absence and
presence of solvent and excipients was monitored by X-ray powder diffraction (XRPD) …

The development of optimized carrier materials for the encapsulation of new high-potency
drugs is frequently hampered by the need for trial-and-error experiments. Combining …

The aim of this study was to investigate the usefulness of the atomic pair-wise distribution
function (PDF) to detect the extension of disorder/amorphousness induced into a crystalline …