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Nanocarrier-based drug combination therapy for glioblastoma
The current achievements in treating glioblastoma (GBM) patients are not sufficient because
many challenges exist, such as tumor heterogeneity, the blood brain barrier, glioma stem …
many challenges exist, such as tumor heterogeneity, the blood brain barrier, glioma stem …
Anticancer drug-loaded hydrogels as drug delivery systems for the local treatment of glioblastoma
Among central nervous system tumors, Glioblastoma (GBM) is the most common, aggressive
and neurological destructive primary brain tumor in adults. Standard care therapy for GBM …
and neurological destructive primary brain tumor in adults. Standard care therapy for GBM …
Rationally designed drug delivery systems for the local treatment of resected glioblastoma
Glioblastoma (GBM) is a particularly aggressive brain cancer associated with high
recurrence and poor prognosis. The standard of care, surgical resection followed by …
recurrence and poor prognosis. The standard of care, surgical resection followed by …
[HTML][HTML] Engineered smart materials for RNA based molecular therapy to treat Glioblastoma
Glioblastoma (GBM) is an aggressive malignancy of the central nervous system (CNS) that
remains incurable despite the multitude of improvements in cancer therapeutics. The …
remains incurable despite the multitude of improvements in cancer therapeutics. The …
Tailoring the multi-functional properties of phospholipids for simple to complex self-assemblies
The unique interfacial properties, huge diversity, and biocompatible nature of phospholipids
make them an attractive pharmaceutical excipient. The amphiphilic nature of these …
make them an attractive pharmaceutical excipient. The amphiphilic nature of these …
Nanotherapeutic treatment of the invasive glioblastoma tumor microenvironment
Glioblastoma (GBM) is the most common malignant adult brain cancer with no curative
treatment strategy. A significant hurdle in GBM treatment is effective therapeutic delivery to …
treatment strategy. A significant hurdle in GBM treatment is effective therapeutic delivery to …
Lauroyl-gemcitabine-loaded lipid nanocapsule hydrogel for the treatment of glioblastoma
C Bastiancich, K Vanvarenberg, B Ucakar… - Journal of Controlled …, 2016 - Elsevier
The local delivery of chemotherapeutic agents is a very promising strategy for the treatment
of glioblastoma (GBM). Gemcitabine is a chemotherapeutic agent that has a different …
of glioblastoma (GBM). Gemcitabine is a chemotherapeutic agent that has a different …
Emerging insights on drug delivery by fatty acid mediated synthesis of lipophilic prodrugs as novel nanomedicines
Many drug molecules that are currently in the market suffer from short half-life, poor
absorption, low specificity, rapid degradation, and resistance development. The design and …
absorption, low specificity, rapid degradation, and resistance development. The design and …
Nanomedicine for glioblastoma: Progress and future prospects
Glioblastoma is the most aggressive form of brain tumor, accounting for the highest mortality
and morbidity rates. Current treatment for patients with glioblastoma includes maximal safe …
and morbidity rates. Current treatment for patients with glioblastoma includes maximal safe …
Multifunctional lipidic nanocarriers for effective therapy of glioblastoma: recent advances in stimuli-responsive, receptor and subcellular targeted approaches
Background Glioblastoma, or glioblastoma multiforme (GBM), remains a fatal cancer type
despite the remarkable progress in understanding the genesis and propagation of the tumor …
despite the remarkable progress in understanding the genesis and propagation of the tumor …