Nanocarrier-based drug combination therapy for glioblastoma

M Zhao, D van Straten, MLD Broekman, V Préat… - …, 2020 - pmc.ncbi.nlm.nih.gov
The current achievements in treating glioblastoma (GBM) patients are not sufficient because
many challenges exist, such as tumor heterogeneity, the blood brain barrier, glioma stem …

Anticancer drug-loaded hydrogels as drug delivery systems for the local treatment of glioblastoma

C Bastiancich, P Danhier, V Préat, F Danhier - Journal of Controlled …, 2016 - Elsevier
Among central nervous system tumors, Glioblastoma (GBM) is the most common, aggressive
and neurological destructive primary brain tumor in adults. Standard care therapy for GBM …

Rationally designed drug delivery systems for the local treatment of resected glioblastoma

C Bastiancich, A Malfanti, V Préat, R Rahman - Advanced drug delivery …, 2021 - Elsevier
Glioblastoma (GBM) is a particularly aggressive brain cancer associated with high
recurrence and poor prognosis. The standard of care, surgical resection followed by …

[HTML][HTML] Engineered smart materials for RNA based molecular therapy to treat Glioblastoma

RR Singh, I Mondal, T Janjua, A Popat… - Bioactive Materials, 2024 - Elsevier
Glioblastoma (GBM) is an aggressive malignancy of the central nervous system (CNS) that
remains incurable despite the multitude of improvements in cancer therapeutics. The …

Tailoring the multi-functional properties of phospholipids for simple to complex self-assemblies

T Waghule, RN Saha, A Alexander, G Singhvi - Journal of Controlled …, 2022 - Elsevier
The unique interfacial properties, huge diversity, and biocompatible nature of phospholipids
make them an attractive pharmaceutical excipient. The amphiphilic nature of these …

Nanotherapeutic treatment of the invasive glioblastoma tumor microenvironment

N Pandey, P Anastasiadis, CP Carney… - Advanced drug delivery …, 2022 - Elsevier
Glioblastoma (GBM) is the most common malignant adult brain cancer with no curative
treatment strategy. A significant hurdle in GBM treatment is effective therapeutic delivery to …

Lauroyl-gemcitabine-loaded lipid nanocapsule hydrogel for the treatment of glioblastoma

C Bastiancich, K Vanvarenberg, B Ucakar… - Journal of Controlled …, 2016 - Elsevier
The local delivery of chemotherapeutic agents is a very promising strategy for the treatment
of glioblastoma (GBM). Gemcitabine is a chemotherapeutic agent that has a different …

Emerging insights on drug delivery by fatty acid mediated synthesis of lipophilic prodrugs as novel nanomedicines

N Fattahi, MA Shahbazi, A Maleki, M Hamidi… - Journal of Controlled …, 2020 - Elsevier
Many drug molecules that are currently in the market suffer from short half-life, poor
absorption, low specificity, rapid degradation, and resistance development. The design and …

Nanomedicine for glioblastoma: Progress and future prospects

I Khan, MH Baig, S Mahfooz, MA Imran, MI Khan… - Seminars in cancer …, 2022 - Elsevier
Glioblastoma is the most aggressive form of brain tumor, accounting for the highest mortality
and morbidity rates. Current treatment for patients with glioblastoma includes maximal safe …

Multifunctional lipidic nanocarriers for effective therapy of glioblastoma: recent advances in stimuli-responsive, receptor and subcellular targeted approaches

MM Hegde, S Prabhu, S Mutalik, A Chatterjee… - Journal of …, 2022 - Springer
Background Glioblastoma, or glioblastoma multiforme (GBM), remains a fatal cancer type
despite the remarkable progress in understanding the genesis and propagation of the tumor …