Background: Bone marrow aspirate concentrate (BMAC) has emerged as a novel treatment
for pathology of the knee. Despite containing a limited number of stem cells, BMAC serves …

Purpose Osteoarthritis (OA) represents a relevant social and economic burden worldwide.“
Mesenchymal stem cells” or, as recently proposed,“medicinal signaling cells”(MSCs) have …

Current tissue regenerative strategies rely mainly on tissue repair by transplantation of the
synthetic/natural implants. However, limitations of the existing strategies have increased the …

Objective Osteoarthritis (OA) is a leading cause of disability in the world. Mesenchymal stem
cells (MSCs) have been studied to treat OA. This review was performed to systematically …

Purpose Bone marrow concentrate (BMC) and platelet-rich plasma (PRP) are used
extensively in regenerative medicine. The aim of this study was to determine differences in …

Background: In the last decade, regenerative therapies have become one of the leading
disease modifying options for treatment of knee osteoarthritis (OA). Still, there is a lack of …

Advanced cell-based therapies are promising approaches for stimulating full regeneration of
cartilage lesions. In addition to a few commercially available medicinal products, several …

Non-surgical treatments are usually the first choice for the management of knee
degeneration, especially in the early osteoarthritis (OA) phase when no clear lesions or …

Purpose To compare the number and properties of bone marrow stromal cells (BMSCs)
collected from bone marrow aspirate concentrate (BMAC) obtained from different harvest …

Osteoarthritis (OA) is the most common type of arthritis found in the United States' population
and is also the most common disease of joints in adults throughout the world with the knee …