Ferroptosis is an iron-dependent and lipid peroxidation-driven cell death cascade, occurring
when there is an imbalance of redox homeostasis in the cell. Nuclear factor erythroid 2 …

Background The homeostasis of metal ions, such as iron, copper, zinc and calcium, in the
brain is crucial for maintaining normal physiological functions. Studies have shown that …

Parkinson's disease (PD) is a gradually progressing neurodegenerative condition that is
marked by a loss of motor coordination along with non-motor features. Although the precise …

The development of sensitive chromogenic chemosensors for sensing Cu 2+ has been
receiving much attention in recent years because of their potential application in clinical …

Copper (Cu) is an essential micronutrient required for the activity of redox‐active enzymes
involved in critical metabolic reactions, signaling pathways, and biological functions …

Copper is an important trace element that is required for essential enzymes. However, due
to its redox activity, copper can also lead to the generation of toxic reactive oxygen species …

Wilson's disease is an autosomal–recessive disorder of copper metabolism caused by
mutations in ATP7B and associated with neurological, psychiatric, ophthalmological and …

Copper-containing enzymes perform fundamental functions by activating dioxygen (O 2) and
therefore allowing chemical energy-transfer for aerobic metabolism. The copper …

The involvement of copper in numerous physiological processes makes this metal ion
essential for human life. Alterations in copper homeostasis might have deleterious …

Alzheimer's disease (AD) is the most common form of dementia, affecting millions of people
around the world. Even though the causes of AD are not completely understood due to its …