The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …

In advanced atherosclerosis (AS), defective function-induced cell death leads to the
formation of the characteristic necrotic core and vulnerable plaque. The forms and …

Hypertension, defined as persistently elevated systolic blood pressure (SBP)> 140 mmHg
and/or diastolic blood pressure (DBP) at least 90 mmHg (International Society of …

Background: Public statements about the effect of smoking on cardiovascular disease are
predominantly based on investigations of coronary heart disease (CHD) and stroke …

The aim of this updated statement is to provide comprehensive and timely evidence-based
recommendations on the prevention of stroke among individuals who have not previously …

Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …

Background and Purpose—This guideline provides an overview of the evidence on
established and emerging risk factors for stroke to provide evidence-based …

Atherosclerosis, the leading cause of death in the developed world and nearly the leading
cause in the develo** world, is associated with systemic risk factors including …

Thioredoxin‐interacting protein (TXNIP) was originally named vitamin D3 upregulated
protein‐1 (VDUP1) because of its ability to bind to thioredoxin (TRX) and inhibit TRX …

As the world endures the coronavirus disease 2019 (COVID-19) pandemic, the conditions of
35 million vulnerable individuals struggling with substance use disorders (SUDs) worldwide …