The biology of VSIG4: Implications for the treatment of immune-mediated inflammatory diseases and cancer
B Liu, L Cheng, H Gao, J Zhang, Y Dong, W Gao… - Cancer Letters, 2023 - Elsevier
V-set and immunoglobulin domain containing 4 (VSIG4), a type I transmembrane receptor
exclusively expressed in a subset of tissue-resident macrophages, plays a pivotal role in …
exclusively expressed in a subset of tissue-resident macrophages, plays a pivotal role in …
Inflammation, immunity, and antigen persistence in post-acute sequelae of SARS-CoV-2 infection
KL Newell, AT Waickman - Current Opinion in Immunology, 2022 - Elsevier
Highlights•Post-acute sequelae of SARS-CoV-2 (PASC) are associated with persistent
inflammation.•The antigens or other immune stimuli driving PASC are still unclear.•PASC …
inflammation.•The antigens or other immune stimuli driving PASC are still unclear.•PASC …
SARS-CoV-2 spike protein induces lung endothelial cell dysfunction and thrombo-inflammation depending on the C3a/C3a receptor signalling
The spike protein of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can
interact with endothelial cells. However, no studies demonstrated the direct effect of the …
interact with endothelial cells. However, no studies demonstrated the direct effect of the …
Elevation of IL‐17 cytokines distinguishes Kawasaki disease from other pediatric inflammatory disorders
KE Brodeur, M Liu, D Ibanez, MJ de Groot… - Arthritis & …, 2024 - Wiley Online Library
Objective Kawasaki disease (KD) is a systemic vasculitis of young children that can lead to
development of coronary artery aneurysms. We aimed to identify diagnostic markers to …
development of coronary artery aneurysms. We aimed to identify diagnostic markers to …
MultiNicheNet: a flexible framework for differential cell-cell communication analysis from multi-sample multi-condition single-cell transcriptomics data
Dysregulated cell-cell communication is a hallmark of many disease phenotypes. Due to
recent advances in single-cell transcriptomics and computational approaches, it is now …
recent advances in single-cell transcriptomics and computational approaches, it is now …
Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19
S Druzak, E Iffrig, BR Roberts, T Zhang… - Nature …, 2023 - nature.com
The pathogenesis of multi-organ dysfunction associated with severe acute SARS-CoV-2
infection remains poorly understood. Endothelial damage and microvascular thrombosis …
infection remains poorly understood. Endothelial damage and microvascular thrombosis …
Pathogenesis, immunology, and immune‐targeted management of the multisystem inflammatory syndrome in children (MIS‐C) or pediatric inflammatory multisystem …
W Feleszko, M Okarska‐Napierała… - Pediatric Allergy and …, 2023 - Wiley Online Library
Multisystem inflammatory syndrome in children (MIS‐C) is a rare, but severe complication of
coronavirus disease 2019 (COVID‐19). It develops approximately 4 weeks after severe …
coronavirus disease 2019 (COVID‐19). It develops approximately 4 weeks after severe …
Immunology of multisystem inflammatory syndrome after COVID-19 in children: a review of the current evidence
Immune responses following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) in children are still under investigation. Even though coronavirus disease 2019 (COVID …
2) in children are still under investigation. Even though coronavirus disease 2019 (COVID …
[HTML][HTML] Thrombotic complications in children with Coronavirus disease 2019 and Multisystem Inflammatory Syndrome of Childhood
R Kumar, MJ Rivkin, L Raffini - Journal of Thrombosis and Haemostasis, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) associated coagulopathy is multifactorial
and involves inflammation driven hypercoagulability, endothelial dysfunction, platelet …
and involves inflammation driven hypercoagulability, endothelial dysfunction, platelet …
Innate immune dysregulation in multisystem inflammatory syndrome in children (MIS-C)
J Isaza-Correa, L Ryan, L Kelly, J Allen, A Melo… - Scientific Reports, 2023 - nature.com
MIS-C is a systemic inflammation disorder with poorly characterised immunopathological
mechanisms. We compared changes in the systemic immune response in children with MIS …
mechanisms. We compared changes in the systemic immune response in children with MIS …