Background It has been recognised for a considerable time-period, that viral respiratory
infections predispose patients to bacterial infections, and that these co-infections have a …

SARS-CoV-2 is a novel coronavirus that infects cells through the angiotensin-converting
enzyme 2 receptor, aided by proteases that prime the spike protein of the virus to enhance …

Understanding how SARS-CoV-2 spreads within the respiratory tract is important to define
the parameters controlling the severity of COVID-19. Here we examine the functional and …

The severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) disease (COVID-19)
pandemic has caused millions of deaths worldwide. Genome-wide association studies …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes a range of
symptoms in infected individuals, from mild respiratory illness to acute respiratory distress …

Elevated levels of cytokines IL-1β and IL-6 are associated with severe COVID-19.
Investigating the underlying mechanisms, we find that while primary human airway epithelia …

Rationale: The incidence and sites of mucus accumulation and molecular regulation of
mucin gene expression in coronavirus (COVID-19) lung disease have not been reported …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causal pathogen of
the ongoing global pandemic of coronavirus disease 2019 (COVID-19). Loss of smell and …

The COVID-19 global epidemic caused by coronavirus has affected the health and other
aspects of life for more than one year. Despite the current pharmacotherapies, there is still …

Host genetic polymorphisms are recognized as a critical determinant of diversity in clinical
symptoms of Coronavirus disease 2019 (COVID-19). Accordingly, this study aimed to …