Bacterial infections are account for the majority of hospital-acquired and community-
acquired infections. The emergency and widespread of drug-resistant pathogens has further …

The rise of drug-resistance has made the deserted clinical requirement to improve of new
classes of antibiotics agents. The development of antibacterial agents with the novel method …

Isatin is an endogenous compound identified in humans that possesses a wide range of
biological activities. Isatin has anxiogenic, sedative, anticonvulsant activities and acts as a …

Hybridization of different pharmacophores from various bioactive substances into a single
molecule is the potential weapon to prevent the drug resistance since this strategy can …

Cu( i )-catalyzed intramolecular oxidative C–H amination of 2-aminoacetophenones: a
convenient route toward isatins - Chemical Communications (RSC Publishing) DOI:10.1039/C3CC44435J …

Parainfluenza-3 virus, Reovirus-1, Sindbis virus, Coxsackie virus B4 and Punta Toro virus)
and HeLa cell culture (Vesicular stomatitis virus, Coxsackie virus B4 and Respiratory …

HIV is the most significant risk factor for many opportunistic infections like fungal,
tuberculosis, etc. The intense media coverage of AIDS puts the public on an emotional roller …

The interaction of isatins, α-amino acids and 1, 6-bismaleimidohexane has been studied. It
was found that for 1'R3-2'-R2-3'-R1-5'-(6-{1'-R3-2'-R2-3'-R1-2, 4', 6'-trioxo-1, 2, 3', 3'a, 4', 5' …

Abstract A series of 1, 3, 5-trisubstituted-2-oxindole derivatives have been synthesized by
reaction of 2, 3-dihydro-2, 3-dioxindol, 1-benzyl-2, 3-dihydro-2, 3-dioxindole and an …

Le travail que nous présentons s' insère dans le cadre des travaux réalisés au laboratoire
de chimie hétérocyclique concernant la synthèse et l'évaluation biologique de l'indoline-2, 3 …