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Role of Oct4 in the early embryo development
G Wu, HR Schöler - Cell Regeneration, 2014 - Springer
Oct4 is a key component of the pluripotency regulatory network, and its reciprocal interaction
with Cdx2 has been shown to be a determinant of either the self-renewal of embryonic stem …
with Cdx2 has been shown to be a determinant of either the self-renewal of embryonic stem …
Curcumin and gastric cancer: A review on mechanisms of action
T Hassanalilou, S Ghavamzadeh, L Khalili - Journal of Gastrointestinal …, 2019 - Springer
Abstract Background and Aim Gastric cancer, as the fourth cause of death in women and
third in men with malignant tumors, is now threatening people's lives worldwide. Natural anti …
third in men with malignant tumors, is now threatening people's lives worldwide. Natural anti …
[HTML][HTML] Post-transcriptional regulation of homeostatic, stressed, and malignant stem cells
BA Chua, I Van Der Werf, C Jamieson, RAJ Signer - Cell stem cell, 2020 - cell.com
Cellular identity is not driven by differences in genomic content but rather by epigenomic,
transcriptomic, and proteomic heterogeneity. Although regulation of the epigenome plays a …
transcriptomic, and proteomic heterogeneity. Although regulation of the epigenome plays a …
Roles of OCT4 in tumorigenesis, cancer therapy resistance and prognosis
ES Villodre, FC Kipper, MB Pereira, G Lenz - Cancer treatment reviews, 2016 - Elsevier
Abstract OCT4 (POU5F1) is a major regulator of cell pluripotency and plays an important
role not only during embryogenesis but also in tumorigenesis. It has been studied in various …
role not only during embryogenesis but also in tumorigenesis. It has been studied in various …
Establishment of totipotency does not depend on Oct4A
G Wu, D Han, Y Gong, V Sebastiano, L Gentile… - Nature cell …, 2013 - nature.com
Oct4A is a core component of the regulatory network of pluripotent cells, and by itself can
reprogram neural stem cells into pluripotent cells in mice and humans. However, its role in …
reprogram neural stem cells into pluripotent cells in mice and humans. However, its role in …
Mediators of induced pluripotency and their role in cancer cells–current scientific knowledge and future perspectives
M Bernhardt, M Galach, D Novak… - Biotechnology journal, 2012 - Wiley Online Library
The discovery that overexpression of the transcription factors Oct4, Sox2, Klf4 and c‐Myc
reprograms differentiated cells into “induced pluripotent stem cells”(iPSCs) has extended …
reprograms differentiated cells into “induced pluripotent stem cells”(iPSCs) has extended …
The endometrium of cycling cows contains populations of putative mesenchymal progenitor cells
J Cabezas, E Lara, P Pacha, D Rojas… - … in Domestic Animals, 2014 - Wiley Online Library
Contents Endometrial stem cells have been identified in humans, mice and pigs. This study
was designed to determine whether the uterine endometrium of cycling cows contains such …
was designed to determine whether the uterine endometrium of cycling cows contains such …
lncRNA PSORS1C3 is regulated by glucocorticoids and fine-tunes OCT4 expression in non-pluripotent cells
F Mirzadeh Azad, M Malakootian, SJ Mowla - Scientific Reports, 2019 - nature.com
OCT4 is a transcription factor known for its regulatory roles in stemness, tumorigenesis and
stress response. Considering its versatile functions, expression of OCT4 is regulated at …
stress response. Considering its versatile functions, expression of OCT4 is regulated at …
Heat‐induced inflammation and its role in esophageal cancer
M Maghsudlu, E Farashahi Yazd - Journal of digestive …, 2017 - Wiley Online Library
Esophageal cancer, the sixth most common cause of death from cancer worldwide, consists
of different histological types and displays various patterns of incidence. Esophageal …
of different histological types and displays various patterns of incidence. Esophageal …
The saffron effects on expression pattern of critical self-renewal genes in adenocarcinoma tumor cell line (AGS)
V Akbarpoor, MN Karimabad, M Mahmoodi… - Gene Reports, 2020 - Elsevier
Abstracts Background The aim of the current study was to determine the effects of various
concentrations of saffron distillate (Crocus sativus) on expression of some self-renewal …
concentrations of saffron distillate (Crocus sativus) on expression of some self-renewal …