The crosstalk between the bone and adipose tissue is known to orchestrate metabolic
homeostasis, but the underlying mechanisms are largely unknown. Herein, we find that …

Adipose tissue inflammation has been implicated in various chronic inflammatory diseases
and cancer. Perivascular adipose tissue (PVAT) surrounds the aorta as an extra layer and …

Abdominal aortic aneurysm (AAA) is strongly correlated with obesity, partially due to the
abnormal expansion of abdominal perivascular adipose tissue (PVAT). Cell death-inducing …

Background After a rotator cuff (RC) tendon tear, the supraspinatus (SS) inflammatory
response induces fatty infiltration (FI). Metformin has the effect of regulating the initial …

Introduction During an immune response, macrophages undergo systematic metabolic
rewiring tailored to support their functions. Branched-chain amino acid (BCAA) metabolism …

Background: Adipocytes play a crucial role in tissue regeneration, contributing to the
restoration of damaged areas and modulating the inflammatory milieu. The modulation of …

Metabolism is the basis for sustaining life and essential to the adaptive evolution of
organisms. With the development of high-throughput sequencing technology, genetic …

Glucocorticoids (GC) s are among the most commonly used clinical drugs worldwide and
are prescribed for many pathologies. They are used to treat chronic inflammatory diseases …