Vaccination with heptavalent pneumococcal conjugate vaccine (PCV7) has significantly
reduced the burden of pneumococcal disease and has had an important public health …

Streptococcus pneumoniae is a Gram-positive bacterial pathogen that colonizes the
mucosal surfaces of the host nasopharynx and upper airway. Through a combination of …

Whole-genome sequencing of 616 asymptomatically carried Streptococcus pneumoniae
isolates was used to study the impact of the 7-valent pneumococcal conjugate vaccine …

Background: The 13-valent pneumococcal conjugate vaccine (PCV13) was introduced for
routine administration to infants and children in 2010 in the United States. We have …

Background Pneumococcal disease is a leading cause of morbidity and mortality worldwide.
The aim of this study was to investigate the association between specific pneumococcal …

Streptococcus pneumoniae is the most common cause of community-acquired pneumonia,
meningitis, and bacteremia in children and adults. Invasive pneumococcal disease (IPD) …

Invasive infections caused by Streptococcus pneumoniae continue to be a major cause of
morbidity and mortality worldwide, especially in children under 5 years of age. In the United …

Background. Little is known about the epidemiology of invasive pneumococcal disease
(IPD) after the introduction of 7-valent pneumococcal conjugate vaccine (PCV7) in Spain …

Background: The long-term effects of selective pressure from conjugate pneumococcal
vaccine on the serotype distribution and antimicrobial resistance of carriage and invasive …

OBJECTIVE: To determine current rates of and trends in hospitalizations for community-
acquired pneumonia (CAP) and CAP-associated complications among children. METHODS …