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Cyclodextrin complexes: Perspective from drug delivery and formulation
Cyclodextrins (CDs) have been widely investigated as a unique pharmaceutical excipient for
past few decades and is still explored for new applications. They are highly versatile …
past few decades and is still explored for new applications. They are highly versatile …
Cyclodextrin in drug delivery: Exploring scaffolds, properties, and cutting-edge applications
Cyclodextrins (CDs) are unique cyclic compounds that can form inclusion complexes via
host–guest complexation with a wide range of molecules, thereby altering their …
host–guest complexation with a wide range of molecules, thereby altering their …
Chitosan/xanthan gum based hydrogels as potential carrier for an antiviral drug: Fabrication, characterization, and safety evaluation
NS Malik, M Ahmad, MU Minhas, R Tulain… - Frontiers in …, 2020 - frontiersin.org
This study investigated the use of pure polymer chitosan (CS), xanthan gum (XG), monomer
2-acrylamido-2-methylpropane sulfonic acid (AMPS) and initiator potassium persulfate …
2-acrylamido-2-methylpropane sulfonic acid (AMPS) and initiator potassium persulfate …
Electrospun formulation of acyclovir/cyclodextrin nanofibers for fast-dissolving antiviral drug delivery
A Celebioglu, T Uyar - Materials Science and Engineering: C, 2021 - Elsevier
Acyclovir is an effective antiviral drug which suffers from limited water solubility and low
bioavailability. However, it is possible to eliminate these limitations by forming inclusion …
bioavailability. However, it is possible to eliminate these limitations by forming inclusion …
The Lord of the NanoRings: Cyclodextrins and the battle against SARS-CoV-2
A handful of singular structures and laws can be observed in nature. They are not always
evident but, once discovered, it seems obvious how to take advantage of them. In chemistry …
evident but, once discovered, it seems obvious how to take advantage of them. In chemistry …
Enhanced photostability and biocompatibility of sunscreen formulation of 2-phenylbenzimidazole-5-sulfonic acid with methyl-beta-cyclodextrin
R Rajamohan, P Muthuraja, C Govindasamy… - Journal of Molecular …, 2023 - Elsevier
Ensuring the photostability of sunscreen lotions is crucial for their effectiveness and safety
when exposed to sunlight. Photostability refers to the ability of a substance to remain stable …
when exposed to sunlight. Photostability refers to the ability of a substance to remain stable …
Enhanced solubility of guanosine by inclusion complexes with cyclodextrin derivatives: Preparation, characterization, and evaluation
This study improves the water solubility and cellular uptake of guanosine (GuN) through an
inclusion complexation with cyclodextrin derivatives (CDs), namely β-cyclodextrin (β-CD) …
inclusion complexation with cyclodextrin derivatives (CDs), namely β-cyclodextrin (β-CD) …
Characteristic of cyclodextrins: Their role and use in the pharmaceutical technology
M Lachowicz, A Stańczak… - Current Drug Targets, 2020 - ingentaconnect.com
About 40% of newly-discovered entities are poorly soluble in water, and this may be an
obstacle in the creation of new drugs. To address this problem, the present review article …
obstacle in the creation of new drugs. To address this problem, the present review article …
Cyclodextrins in antiviral therapeutics and vaccines
The present review describes the various roles of cyclodextrins (CDs) in vaccines against
viruses and in antiviral therapeutics. The first section describes the most commonly studied …
viruses and in antiviral therapeutics. The first section describes the most commonly studied …
Formulation and evaluation of nano based drug delivery system for the buccal delivery of acyclovir
BE Al-Dhubiab, AB Nair, R Kumria, M Attimarad… - Colloids and Surfaces B …, 2015 - Elsevier
Oral bioavailability of acyclovir is limited, primarily because of low permeability across the
gastrointestinal membrane. The purpose of this study is the prospective evaluation of buccal …
gastrointestinal membrane. The purpose of this study is the prospective evaluation of buccal …