Cyclodextrin complexes: Perspective from drug delivery and formulation

S Jacob, AB Nair - Drug development research, 2018 - Wiley Online Library
Cyclodextrins (CDs) have been widely investigated as a unique pharmaceutical excipient for
past few decades and is still explored for new applications. They are highly versatile …

Cyclodextrin in drug delivery: Exploring scaffolds, properties, and cutting-edge applications

P Singh, R Mahar - International Journal of Pharmaceutics, 2024 - Elsevier
Cyclodextrins (CDs) are unique cyclic compounds that can form inclusion complexes via
host–guest complexation with a wide range of molecules, thereby altering their …

Chitosan/xanthan gum based hydrogels as potential carrier for an antiviral drug: Fabrication, characterization, and safety evaluation

NS Malik, M Ahmad, MU Minhas, R Tulain… - Frontiers in …, 2020 - frontiersin.org
This study investigated the use of pure polymer chitosan (CS), xanthan gum (XG), monomer
2-acrylamido-2-methylpropane sulfonic acid (AMPS) and initiator potassium persulfate …

Electrospun formulation of acyclovir/cyclodextrin nanofibers for fast-dissolving antiviral drug delivery

A Celebioglu, T Uyar - Materials Science and Engineering: C, 2021 - Elsevier
Acyclovir is an effective antiviral drug which suffers from limited water solubility and low
bioavailability. However, it is possible to eliminate these limitations by forming inclusion …

Enhanced photostability and biocompatibility of sunscreen formulation of 2-phenylbenzimidazole-5-sulfonic acid with methyl-beta-cyclodextrin

R Rajamohan, P Muthuraja, C Govindasamy… - Journal of Molecular …, 2023 - Elsevier
Ensuring the photostability of sunscreen lotions is crucial for their effectiveness and safety
when exposed to sunlight. Photostability refers to the ability of a substance to remain stable …

The Lord of the NanoRings: Cyclodextrins and the battle against SARS-CoV-2

PF Garrido, M Calvelo, A Blanco-Gonzalez… - International journal of …, 2020 - Elsevier
A handful of singular structures and laws can be observed in nature. They are not always
evident but, once discovered, it seems obvious how to take advantage of them. In chemistry …

Formulation and evaluation of nano based drug delivery system for the buccal delivery of acyclovir

BE Al-Dhubiab, AB Nair, R Kumria, M Attimarad… - Colloids and Surfaces B …, 2015 - Elsevier
Oral bioavailability of acyclovir is limited, primarily because of low permeability across the
gastrointestinal membrane. The purpose of this study is the prospective evaluation of buccal …

β-cyclodextrin chitosan-based hydrogels with tunable pH-responsive properties for controlled release of acyclovir: design, characterization, safety, and …

NS Malik, M Ahmad, MS Alqahtani, A Mahmood… - Drug Delivery, 2021 - Taylor & Francis
In this work, series of pH-responsive hydrogels (FMA1–FMA9) were synthesized,
characterized, and evaluated as potential carrier for oral delivery of an antiviral drug …

Cyclodextrins in the antiviral therapy

L Jicsinszky, K Martina, G Cravotto - Journal of drug delivery science and …, 2021 - Elsevier
The main antiviral drug-cyclodextrin interactions, changes in physicochemical and
physiological properties of the most commonly used virucides are summarized. The …

Enhanced solubility of guanosine by inclusion complexes with cyclodextrin derivatives: Preparation, characterization, and evaluation

S Mohandoss, R Atchudan, TNJI Edison… - Carbohydrate …, 2019 - Elsevier
This study improves the water solubility and cellular uptake of guanosine (GuN) through an
inclusion complexation with cyclodextrin derivatives (CDs), namely β-cyclodextrin (β-CD) …