The coagulopathy of trauma: a review of mechanisms

JR Hess, K Brohi, RP Dutton, CJ Hauser… - Journal of Trauma …, 2008 - journals.lww.com
Background: Bleeding is the most frequent cause of preventable death after severe injury.
Coagulopathy associated with severe injury complicates the control of bleeding and is …

Efficacy of red blood cell transfusion in the critically ill: a systematic review of the literature

PE Marik, HL Corwin - Critical care medicine, 2008 - journals.lww.com
Background: Red blood cell (RBC) transfusions are common in intensive care unit, trauma,
and surgical patients. However, the hematocrit that should be maintained in any particular …

Clinical practice guideline: red blood cell transfusion in adult trauma and critical care

LM Napolitano, S Kurek, FA Luchette… - Critical care …, 2009 - journals.lww.com
Objective: To develop a clinical practice guideline for red blood cell transfusion in adult
trauma and critical care. Design: Meetings, teleconferences and electronic-based …

Surgical outcomes and transfusion of minimal amounts of blood in the operating room

VA Ferraris, DL Davenport, SP Saha… - Archives of …, 2012 - jamanetwork.com
Objective To examine outcomes in patients who receive small amounts of intraoperative
blood transfusion. Design Longitudinal, uncontrolled observational study evaluating results …

Complications of massive transfusion

KC Sihler, LM Napolitano - Chest, 2010 - Elsevier
Massive transfusion (MT) is a lifesaving treatment of hemorrhagic shock, but can be
associated with significant complications. The lethal triad of acidosis, hypothermia, and …

Massive transfusion protocols: the role of aggressive resuscitation versus product ratio in mortality reduction

DJ Riskin, TC Tsai, L Riskin… - Journal of the American …, 2009 - Elsevier
BACKGROUND: Exsanguinating hemorrhage necessitating massive blood product
transfusion is associated with high mortality rates. Recent data suggest that altering the fresh …

Postinjury multiple organ failure

D Dewar, FA Moore, EE Moore, Z Balogh - Injury, 2009 - Elsevier
Postinjury multiple organ failure (MOF) became prevalent as the improvements in critical
care during the 1970s made it possible to keep trauma patients alive with single organ …

Extracorporeal membrane oxygenation in severe trauma patients with bleeding shock

M Arlt, A Philipp, S Voelkel, L Rupprecht, T Mueller… - Resuscitation, 2010 - Elsevier
AIM OF THE STUDY: Death to trauma is caused by disastrous injuries on scene, bleeding
shock or acute respiratory failure (ARDS) induced by trauma and massive blood transfusion …

[HTML][HTML] A review of blood substitutes: examining the history, clinical trial results, and ethics of hemoglobin-based oxygen carriers

JY Chen, M Scerbo, G Kramer - Clinics, 2009 - SciELO Brasil
The complications associated with acquiring and storing whole blood for transfusions have
launched substantial efforts to develop a blood substitute. The history of these efforts …

Epidemiology and risk factors of sepsis after multiple trauma: an analysis of 29,829 patients from the Trauma Registry of the German Society for Trauma Surgery

A Wafaisade, R Lefering, B Bouillon… - Critical care …, 2011 - journals.lww.com
Objectives: The objectives of this study were 1) to assess potential changes in the incidence
and outcome of sepsis after multiple trauma in Germany between 1993 and 2008 and 2) to …