Limitations in mobility are common in persons with intellectual disabilities (ID). As balance
and gait capacities are key aspects of mobility, the prevalence of balance and gait problems …

[Purpose] To describe (1) the current knowledge on gait and postural control in individuals
with Down syndrome in terms of spatiotemporal, kinematics and kinetics, and (2) relevant …

Autoantibodies against leucine-rich glioma inactivated 1 (LGI1) are found in patients with
limbic encephalitis and focal seizures. Here, we generate patient-derived monoclonal …

Abstract Background People with Down syndrome (DS) usually display reduced physical
fitness (aerobic capacity, muscle strength and abnormal body composition), motor …

Background Musculoskeletal complications of Down syndrome (DS) are common but
infrequently reported. The combination of ligamentous laxity and low muscle tone …

Down syndrome (DS) is the most prevalent form of mental retardation caused by genetic
abnormalities in humans. This has been successfully modeled in mice to generate the …

The literature is bereft of information about the age at which infants with Down syndrome
(DS) acquire motor skills and the percentage of infants that do so by the age of 12 months …

Carbon fiber running-specific prostheses (RSPs) have allowed individuals with lower
extremity amputation (ILEA) to participate in running. It has been established that as running …

Abstract Background Prader-Willi (PWS) and Down Syndrome (DS) are two genetic
disorders characterised by some common clinical and functional features. A quantitative …

Background Although physical fitness has been suggested to improve physical and
psychosocial health for a variety of population profiles, there is a lack of information about …