Metabolic engineering: methodologies and applications

MJ Volk, VG Tran, SI Tan, S Mishra, Z Fatma… - Chemical …, 2022‏ - ACS Publications
Metabolic engineering aims to improve the production of economically valuable molecules
through the genetic manipulation of microbial metabolism. While the discipline is a little over …

Fuelling the future: microbial engineering for the production of sustainable biofuels

JC Liao, L Mi, S Pontrelli, S Luo - Nature Reviews Microbiology, 2016‏ - nature.com
Global climate change linked to the accumulation of greenhouse gases has caused
concerns regarding the use of fossil fuels as the major energy source. To mitigate climate …

Antimicrobial gold nanoclusters

K Zheng, MI Setyawati, DT Leong, J **e - ACS nano, 2017‏ - ACS Publications
Bulk gold (Au) is known to be chemically inactive. However, when the size of Au
nanoparticles (Au NPs) decreases to close to 1 nm or sub-nanometer dimensions, these …

Bio-jet fuel conversion technologies

WC Wang, L Tao - Renewable and Sustainable Energy Reviews, 2016‏ - Elsevier
Biomass-derived jet (bio-jet) fuel has become a key element in the aviation industry׳ s
strategy to reduce operating costs and environmental impacts. Researchers from the oil …

Sustainable oil palm industry: The possibilities

R Khatun, MIH Reza, M Moniruzzaman… - … and Sustainable Energy …, 2017‏ - Elsevier
Cruel oil or green gold is a dilemma for the oil palm industry. The oil palm industry (planting
and milling) has a devastating impact on the environment and ecosystems. Oil palm …

NADPH-generating systems in bacteria and archaea

SK Spaans, RA Weusthuis, J Van Der Oost… - Frontiers in …, 2015‏ - frontiersin.org
Reduced nicotinamide adenine dinucleotide phosphate (NADPH) is an essential electron
donor in all organisms. It provides the reducing power that drives numerous anabolic …

Systems metabolic engineering of microorganisms for natural and non-natural chemicals

JW Lee, D Na, JM Park, J Lee, S Choi… - Nature chemical biology, 2012‏ - nature.com
Growing concerns over limited fossil resources and associated environmental problems are
motivating the development of sustainable processes for the production of chemicals, fuels …

Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols

JL Avalos, GR Fink, G Stephanopoulos - Nature biotechnology, 2013‏ - nature.com
Efforts to improve the production of a compound of interest in Saccharomyces cerevisiae
have mainly involved engineering or overexpression of cytoplasmic enzymes. We show that …

Transformation of biomass into commodity chemicals using enzymes or cells

AJJ Straathof - Chemical reviews, 2014‏ - ACS Publications
Biomass can be classified broadly as all the matter on the earth's surface of recent biological
origin. 1 Biomass includes plant materials such as trees, grasses, agricultural crops, algal …

Cell‐free metabolic engineering: biomanufacturing beyond the cell

QM Dudley, AS Karim, MC Jewett - Biotechnology journal, 2015‏ - Wiley Online Library
Industrial biotechnology and microbial metabolic engineering are poised to help meet the
growing demand for sustainable, low‐cost commodity chemicals and natural products, yet …