The menopause transition: signs, symptoms, and management options
Context Menopause, the permanent cessation of menses, reflects oocyte depletion and loss
of gonadal steroids. It is preceded by a transition state, the perimenopause, which is …
of gonadal steroids. It is preceded by a transition state, the perimenopause, which is …
Hormone-replacement therapy: current thinking
For several decades, the role of hormone-replacement therapy (HRT) has been debated.
Early observational data on HRT showed many benefits, including a reduction in coronary …
Early observational data on HRT showed many benefits, including a reduction in coronary …
Association of menopausal hormone therapy with breast cancer incidence and mortality during long-term follow-up of the women's health initiative randomized clinical …
Importance The influence of menopausal hormone therapy on breast cancer remains
unsettled with discordant findings from observational studies and randomized clinical trials …
unsettled with discordant findings from observational studies and randomized clinical trials …
2016 IMS Recommendations on women's midlife health and menopause hormone therapy
RJ Baber, N Panay, A Fenton - Climacteric, 2016 - Taylor & Francis
Abstract The International Menopause Society (IMS) has produced these new 2016
recommendations on women's midlife health and menopause hormone therapy (MHT) to …
recommendations on women's midlife health and menopause hormone therapy (MHT) to …
[HTML][HTML] Menopausal hormone therapy and long-term all-cause and cause-specific mortality: the Women's Health Initiative randomized trials
Importance Health outcomes from the Women's Health Initiative Estrogen Plus Progestin
and Estrogen-Alone Trials have been reported, but previous publications have generally not …
and Estrogen-Alone Trials have been reported, but previous publications have generally not …
Treatment of symptoms of the menopause: an endocrine society clinical practice guideline
Objective: The objective of this document is to generate a practice guideline for the
management and treatment of symptoms of the menopause. Participants: The Treatment of …
management and treatment of symptoms of the menopause. Participants: The Treatment of …
Overweight, obesity, and postmenopausal invasive breast cancer risk: a secondary analysis of the women's health initiative randomized clinical trials
Importance More than two-thirds of US women are overweight or obese, placing them at
increased risk for postmenopausal breast cancer. Objective To investigate in this secondary …
increased risk for postmenopausal breast cancer. Objective To investigate in this secondary …
Menopausal hormone therapy and health outcomes during the intervention and extended poststop** phases of the Women's Health Initiative randomized trials
Importance Menopausal hormone therapy continues in clinical use but questions remain
regarding its risks and benefits for chronic disease prevention. Objective To report a …
regarding its risks and benefits for chronic disease prevention. Objective To report a …
Estrogen receptors and the aging brain
The female sex hormone estrogen has been ascribed potent neuroprotective properties. It
signals by binding and activating estrogen receptors that, depending on receptor subtype …
signals by binding and activating estrogen receptors that, depending on receptor subtype …
Risks, benefits, and treatment modalities of menopausal hormone therapy: current concepts
Menopausal hormone therapy (HT) prescribing practices have evolved over the last few
decades guided by the changing understanding of the treatment's risks and benefits. Since …
decades guided by the changing understanding of the treatment's risks and benefits. Since …