Predicting neurosurgical outcomes in focal epilepsy patients using computational modelling

N Sinha, J Dauwels, M Kaiser, SS Cash… - Brain, 2017 - academic.oup.com
Abstract See Eissa and Schevon (doi: 10.1093/aww332) for a scientific commentary on this
article. Surgery can be a last resort for patients with intractable, medically refractory epilepsy …

FitzHugh–Nagumo oscillators on complex networks mimic epileptic-seizure-related synchronization phenomena

M Gerster, R Berner, J Sawicki, A Zakharova… - … Journal of Nonlinear …, 2020 - pubs.aip.org
We study patterns of partial synchronization in a network of FitzHugh–Nagumo oscillators
with empirical structural connectivity measured in human subjects. We report the …

Epilepsy as a manifestation of a multistate network of oscillatory systems

S Kalitzin, G Petkov, P Suffczynski, V Grigorovsky… - Neurobiology of …, 2019 - Elsevier
The human brain, largely accepted as the most complex biological system known, is still far
from being understood in its parts or as a whole. More specifically, biological mechanisms of …

Estimation of brain network ictogenicity predicts outcome from epilepsy surgery

M Goodfellow, C Rummel, E Abela, MP Richardson… - Scientific reports, 2016 - nature.com
Surgery is a valuable option for pharmacologically intractable epilepsy. However, significant
post-operative improvements are not always attained. This is due in part to our incomplete …

[KNIHA][B] Elliptic partial differential equations

VA Volʹpert - 2014 - Springer
If we had to formulate in one sentence what this book is about, it might be “How partial
differential equations can help to understand heat explosion, tumor growth or evolution of …

Statistical properties and predictability of extreme epileptic events

NS Frolov, VV Grubov, VA Maksimenko, A Lüttjohann… - Scientific reports, 2019 - nature.com
The use of extreme events theory for the analysis of spontaneous epileptic brain activity is a
relevant multidisciplinary problem. It allows deeper understanding of pathological brain …

Structural connectivity based whole brain modelling in epilepsy

PN Taylor, M Kaiser, J Dauwels - Journal of neuroscience methods, 2014 - Elsevier
Epilepsy is a neurological condition characterised by the recurrence of seizures. During
seizures multiple brain areas can behave abnormally. Rather than considering each …

Seizure generation: the role of nodes and networks

JR Terry, O Benjamin, MP Richardson - Epilepsia, 2012 - Wiley Online Library
The longstanding dichotomy between the concepts of “focal” and “primary generalized”
epilepsy has become increasingly blurred, raising fundamental questions about the nature …

A computational study of stimulus driven epileptic seizure abatement

PN Taylor, Y Wang, M Goodfellow, J Dauwels… - PLOS …, 2014 - journals.plos.org
Active brain stimulation to abate epileptic seizures has shown mixed success. In spike-wave
(SW) seizures, where the seizure and background state were proposed to coexist, single …

An optimal strategy for epilepsy surgery: Disruption of the rich-club?

MA Lopes, MP Richardson, E Abela… - PLoS computational …, 2017 - journals.plos.org
Surgery is a therapeutic option for people with epilepsy whose seizures are not controlled by
anti-epilepsy drugs. In pre-surgical planning, an array of data modalities, often including …