As somatic cells are converted into induced pluripotent stem cells (iPSCs), their chromatin is
remodeled to a pluripotent configuration with unique euchromatin-to-heterochromatin ratios …

The concept of cellular plasticity is particularly apt in early embryonic development, where
there is a tug-of-war between the stability and flexibility of cell identity. This balance is …

Objective: The present study aimed to establish an induced pluripotent stem cell (iPSC) line
from acute myelogenous leukemia (AML) cells in vitro and identify their biological …

Background: Stemness markers play critical roles in the maintenance of key properties of
embryonic stem cells (ESCs), including the pluripotency, stemness state, and self-renewal …

Objective. To explore the relationship between CTCFL and DPPA2 and validate the positive
role of CTCFL/DPPA2 in cell malignant behaviors in gastric cancer. Methods. We predicted …

Gastric cancer (GC) is the fourth most common cause of mortality and the fifth for incidence,
globally. Diagnosis, early prognosis, and therapy remains challenging for this condition, and …

Dysregulation of the ubiquitin–proteasome pathway is strongly associated with cancer
initiation and progression. Speckle-type POZ (pox virus and zinc finger protein) protein …

2021-06-18 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

2020-12-11 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

New biomarkers are urgently needed to detect pancreatic ductal adenocarcinoma (PDAC) at
an earlier stage and subsequently individualize treatment strategies. Here, we identified a …