The rise of non-tuberculosis mycobacterial lung disease

CN Ratnatunga, VP Lutzky, A Kupz, DL Doolan… - Frontiers in …, 2020 - frontiersin.org
The incidence and number of deaths from non-tuberculous mycobacterial (NTM) disease
have been steadily increasing globally. These lesser known “cousins” of Mycobacterium …

Nontuberculous mycobacterial lung disease caused by Mycobacterium avium complex - disease burden, unmet needs, and advances in treatment developments

J van Ingen, M Obradovic, M Hassan… - Expert Review of …, 2021 - Taylor & Francis
Introduction Nontuberculous mycobacterial (NTM) lung disease (LD) is the most common
clinical manifestation of NTM infection and is a growing health concern. Up to 85% of NTM …

Arginine-mediated gut microbiome remodeling promotes host pulmonary immune defense against nontuberculous mycobacterial infection

YJ Kim, JY Lee, JJ Lee, SM Jeon, P Silwal, IS Kim… - Gut …, 2022 - Taylor & Francis
Nontuberculous mycobacterial pulmonary diseases (NTM-PDs) are emerging as global
health threats with issues of antibiotic resistance. Accumulating evidence suggests that the …

Nontuberculous mycobacteria in drinking water systems–the challenges of characterization and risk mitigation

K Dowdell, SJ Haig, LJ Caverly, Y Shen… - Current opinion in …, 2019 - Elsevier
Highlights•Nontuberculous mycobacteria (NTM) are pervasive in drinking water
systems.•NTM are resistant to disinfection and are found in pipe and showerhead …

Understanding the development of tuberculous granulomas: insights into host protection and pathogenesis, a review in humans and animals

J Lyu, DE Narum, SL Baldwin, SE Larsen… - Frontiers in …, 2024 - frontiersin.org
Granulomas, organized aggregates of immune cells which form in response to
Mycobacterium tuberculosis (Mtb), are characteristic but not exclusive of tuberculosis (TB) …

Modulating macrophage function to reinforce host innate resistance against Mycobacterium avium complex infection

HE Park, W Lee, S Choi, M Jung, MK Shin… - Frontiers in …, 2022 - frontiersin.org
Mycobacterium avium complex (MAC) is the main causative agent of infectious diseases in
humans among nontuberculous mycobacteria (NTM) that are ubiquitous organisms found in …

Host immune response and novel diagnostic approach to NTM infections

Y Abe, K Fukushima, Y Hosono, Y Matsumoto… - International Journal of …, 2020 - mdpi.com
The incidence and prevalence of non-tuberculous mycobacteria (NTM) infections are
steadily increasing worldwide, partially due to the increased incidence of …

Characterization of integrated prophages within diverse species of clinical nontuberculous mycobacteria

C Glickman, SM Kammlade, NA Hasan, LE Epperson… - Virology journal, 2020 - Springer
Background Nontuberculous mycobacterial (NTM) infections are increasing in prevalence,
with current estimates suggesting that over 100,000 people in the United States are affected …

Evaluation of the STANDARD M10 MDR-TB and MTB/NTM assays for the detection of Mycobacterium tuberculosis, rifampicin and isoniazid resistance, and …

B Luukinen, J Aittoniemi… - Journal of Clinical …, 2024 - journals.asm.org
Rapid detection is crucial for tuberculosis (TB) control. GeneXpert (Cepheid) is a widely
used PCR system, known for its simplicity, random access, and point-of-care compatibility …

Donor-defined mesenchymal stem cell antimicrobial potency against nontuberculous mycobacterium

TL Bonfield, MT Sutton, DR Fletcher… - Stem Cells …, 2021 - academic.oup.com
Chronic nontuberculous mycobacterial infections with Mycobacterium avium and
Mycobacterium intracellulare complicate bronchiectasis, chronic obstructive airway disease …