Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently
The amino acid sequence of a protein affects both its structure and its function. Thus, the
ability to modify the sequence, and hence the structure and activity, of individual proteins in …
ability to modify the sequence, and hence the structure and activity, of individual proteins in …
Microbial degradation of glyphosate herbicides
AV Sviridov, TV Shushkova, IT Ermakova… - Applied biochemistry …, 2015 - Springer
This review analyzes the issues associated with biodegradation of glyphosate (N-
(phosphonomethyl) glycine), one of the most widespread herbicides. Glyphosate can …
(phosphonomethyl) glycine), one of the most widespread herbicides. Glyphosate can …
Utilization of glyphosate as phosphate source: biochemistry and genetics of bacterial carbon-phosphorus lyase
B Hove-Jensen, DL Zechel… - … and Molecular Biology …, 2014 - Am Soc Microbiol
After several decades of use of glyphosate, the active ingredient in weed killers such as
Roundup, in fields, forests, and gardens, the biochemical pathway of transformation of …
Roundup, in fields, forests, and gardens, the biochemical pathway of transformation of …
Aldo-keto Reductase Metabolizes Glyphosate and Confers Glyphosate Resistance in Echinochloa colona
Glyphosate, the most commonly used herbicide in the world, controls a wide range of plant
species, mainly because plants have little capacity to metabolize (detoxify) glyphosate …
species, mainly because plants have little capacity to metabolize (detoxify) glyphosate …
Molecular basis of glyphosate resistance–different approaches through protein engineering
Glyphosate (N‐phosphonomethyl‐glycine) is the most widely used herbicide in the world:
glyphosate‐based formulations exhibit broad‐spectrum herbicidal activity with minimal …
glyphosate‐based formulations exhibit broad‐spectrum herbicidal activity with minimal …
Glyphosate degradation in glyphosate-resistant and-susceptible crops and weeds
SO Duke - Journal of agricultural and food chemistry, 2011 - ACS Publications
High levels of aminomethylphosphonic acid (AMPA), the main glyphosate metabolite, have
been found in glyphosate-treated, glyphosate-resistant (GR) soybean, apparently due to …
been found in glyphosate-treated, glyphosate-resistant (GR) soybean, apparently due to …
Glyphosate-degrading behavior of five bacterial strains isolated from stream biofilms
F Rossi, L Carles, F Donnadieu, I Batisson… - Journal of Hazardous …, 2021 - Elsevier
The present study investigates the individual degrading behavior of bacterial strains isolated
from glyphosate-degrading stream biofilms. In this aim, biofilms were subjected to …
from glyphosate-degrading stream biofilms. In this aim, biofilms were subjected to …
[HTML][HTML] Computational modelling provides insight into the effects of glyphosate on the shikimate pathway in the human gut microbiome
R Mesnage, MN Antoniou - Current research in toxicology, 2020 - Elsevier
The herbicide active ingredient glyphosate can affect the growth of microorganisms, which
rely on the shikimate pathway for aromatic amino acid biosynthesis. However, it is uncertain …
rely on the shikimate pathway for aromatic amino acid biosynthesis. However, it is uncertain …
Flavoprotein oxidases: classification and applications
This review provides an overview of oxidases that utilise a flavin cofactor for catalysis. This
class of oxidative flavoenzymes has shown to harbour a large number of biotechnologically …
class of oxidative flavoenzymes has shown to harbour a large number of biotechnologically …
New biotech applications from evolved D-amino acid oxidases
d-Amino acid oxidase (DAAO) is a well-known flavoenzyme that catalyzes the oxygen-
dependent oxidative deamination of amino acid D-isomers with absolute stereospecificity …
dependent oxidative deamination of amino acid D-isomers with absolute stereospecificity …