CRISPR diagnostics (CRISPR-Dx) offer a wide range of enhancements compared to
traditional nanobiosensors by taking advantage of the excellent trans-cleavage activity of the …

Spatial and temporal control over chemical and biological processes plays a key role in life,
where the whole is often much more than the sum of its parts. Quite trivially, the molecules of …

In vivo medical imaging has made great progress due to advances in the engineering of
imaging devices and developments in the chemistry of imaging probes. Several modalities …

Biosensors based on the principle of Förster (or fluorescence) resonance energy transfer
(FRET) have shed new light on the spatiotemporal dynamics of signaling molecules. Among …

Imaging of living cells and tissue is now common in many fields of the life and physical
sciences, and is instrumental in revealing a great deal about cellular dynamics and function …

This protocol describes procedures for performing fluorescence resonance energy transfer
(FRET) microscopy analysis by three different methods: acceptor photobleaching, sensitized …

Abstract Within the Design-Build-Test Cycle for strain engineering, rapid product detection
and selection strategies remain challenging and limit overall throughput. Here we …

This study describes the first instance of the use of two differently sized Au nanoparticles (Au
NPs), acting separately as donor and acceptor, in homogeneous photoluminescence …

Historically, Lewis acidic metal coordination complexes have played a pivotal and defining
role in the broad field of molecular recognition and more specifically in the sensing and …

Background Molecular oxygen (O 2) is one of the key metabolites of all obligate and
facultative aerobic pro-and eukaryotes. It plays a fundamental role in energy homeostasis …