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Collective cell migration: a physics perspective
Cells have traditionally been viewed either as independently moving entities or as
somewhat static parts of tissues. However, it is now clear that in many cases, multiple cells …
somewhat static parts of tissues. However, it is now clear that in many cases, multiple cells …
Tumor cell migration in complex microenvironments
Tumor cell migration is essential for invasion and dissemination from primary solid tumors
and for the establishment of lethal secondary metastases at distant organs. In vivo and in …
and for the establishment of lethal secondary metastases at distant organs. In vivo and in …
DNA hydrogel with aptamer-toehold-based recognition, cloaking, and decloaking of circulating tumor cells for live cell analysis
Circulating tumor cells (CTCs) contain molecular information on the primary tumor and can
be used for predictive cancer diagnostics. Capturing rare live CTCs and their quantification …
be used for predictive cancer diagnostics. Capturing rare live CTCs and their quantification …
Elucidating mechanical transition effects of invading cancer cells with a subnucleus-scaled microfluidic serial dimensional modulation device
Mechanical boundaries that define and regulate biological processes, such as cell-cell
junctions and dense extracellular matrix networks, exist throughout the physiological …
junctions and dense extracellular matrix networks, exist throughout the physiological …
Controlling matrix stiffness and topography for the study of tumor cell migration
CM Kraning-Rush, CA Reinhart-King - Cell adhesion & migration, 2012 - Taylor & Francis
Cellular studies have long been performed on the bench top, within Petri dishes and flasks
that expose cells to surroundings that differ greatly from their native environment. The …
that expose cells to surroundings that differ greatly from their native environment. The …
TRPM4 channel is involved in regulating epithelial to mesenchymal transition, migration, and invasion of prostate cancer cell lines
Abstract Transient Receptor Potential Melastatin 4 (TRPM4) is a Ca2+‐activated and voltage‐
dependent monovalent cation channel, which depolarizes the plasma cell membrane …
dependent monovalent cation channel, which depolarizes the plasma cell membrane …
Minimization of thermodynamic costs in cancer cell invasion
Metastasis, the truly lethal aspect of cancer, occurs when metastatic cancer cells in a tumor
break through the basement membrane and penetrate the extracellular matrix. We show that …
break through the basement membrane and penetrate the extracellular matrix. We show that …
Combination of microfluidic chips and biosensing for the enrichment of circulating tumor cells
J Shi, C Zhao, M Shen, Z Chen, J Liu, S Zhang… - Biosensors and …, 2022 - Elsevier
It has been reported that more than 90% of cancer patients are died from cancer metastasis.
Circulating tumor cells (CTCs) could detach from solid tumors to form new lesions via blood …
Circulating tumor cells (CTCs) could detach from solid tumors to form new lesions via blood …
Fabrication of substrates with defined mechanical properties and topographical features for the study of cell migration
Both substrate topography and substrate mechanical properties are known to influence cell
behavior, but little is known about how they act in concert. Here, a method is presented to …
behavior, but little is known about how they act in concert. Here, a method is presented to …
Optimal quantification of contact inhibition in cell populations
Contact inhibition refers to a reduction in the rate of cell migration and/or cell proliferation in
regions of high cell density. Under normal conditions, contact inhibition is associated with …
regions of high cell density. Under normal conditions, contact inhibition is associated with …