[HTML][HTML] Identification of cyclin protein using gradient boost decision tree algorithm

H Zulfiqar, SS Yuan, QL Huang, ZJ Sun, FY Dao… - Computational and …, 2021 - Elsevier
Cyclin proteins are capable to regulate the cell cycle by forming a complex with cyclin-
dependent kinases to activate cell cycle. Correct recognition of cyclin proteins could provide …

iMPT‐FDNPL: Identification of Membrane Protein Types with Functional Domains and a Natural Language Processing Approach

W Chen, L Chen, Q Dai - Computational and Mathematical …, 2021 - Wiley Online Library
Membrane protein is an important kind of proteins. It plays essential roles in several cellular
processes. Based on the intramolecular arrangements and positions in a cell, membrane …

Two phase feature-ranking for new soil dataset for Coxiella burnetii persistence and classification using machine learning models

F Ahmad, MU Ghani Khan, A Tahir, MY Tipu… - Scientific Reports, 2023 - nature.com
Coxiella burnetii (Cb) is a hardy, stealth bacterial pathogen lethal for humans and animals.
Its tremendous resistance to the environment, ease of propagation, and incredibly low …

Detection of transcription factors binding to methylated DNA by deep recurrent neural network

H Li, Y Gong, Y Liu, H Lin, G Wang - Briefings in bioinformatics, 2022 - academic.oup.com
Transcription factors (TFs) are proteins specifically involved in gene expression regulation. It
is generally accepted in epigenetics that methylated nucleotides could prevent the TFs from …

[HTML][HTML] Interpretable CRISPR/Cas9 off-target activities with mismatches and indels prediction using BERT

Y Luo, Y Chen, HZ **e, W Zhu, G Zhang - Computers in Biology and …, 2024 - Elsevier
Off-target effects of CRISPR/Cas9 can lead to suboptimal genome editing outcomes.
Numerous deep learning-based approaches have achieved excellent performance for off …

Identifying key soil characteristics for Francisella tularensis classification with optimized Machine learning models

F Ahmad, K Javed, A Tahir, MUG Khan, M Abbas… - Scientific Reports, 2024 - nature.com
Francisella tularensis (Ft) poses a significant threat to both animal and human populations,
given its potential as a bioweapon. Current research on the classification of this pathogen …

A new sequential forward feature selection (SFFS) algorithm for mining best topological and biological features to predict protein complexes from protein–protein …

H Younis, MW Anwar, MUG Khan, A Sikandar… - Interdisciplinary …, 2021 - Springer
Protein–protein interaction plays an important role in the understanding of biological
processes in the body. A network of dynamic protein complexes within a cell that regulates …

Detecting blood methylation signatures in response to childhood cancer radiotherapy via machine learning methods

Z Li, W Guo, S Ding, K Feng, L Lu, T Huang, Y Cai - Biology, 2022 - mdpi.com
Simple Summary Radiotherapy for cancer patients can cause abnormal DNA methylation.
We developed a computational workflow that can identify crucial methylation alterations …

Pseudo-188D: Phage Protein Prediction Based on a Model of Pseudo-188D

X Gu, L Guo, B Liao, Q Jiang - Frontiers in Genetics, 2021 - frontiersin.org
Phages have seriously affected the biochemical systems of the world, and not only are
phages related to our health, but medical treatments for many cancers and skin infections …

[PDF][PDF] Potential Role of Zoonoses in Bioterrorism

T Iqbal, A Ahmad, MT Naveed… - Zoonosis, Unique …, 2023 - uniquescientificpublishers.com
The presence of zoonotic pathogens in bioterrorism poses a serious danger to worldwide
health and safety. Zoonotic diseases, which can be transmitted from animals to humans, are …